Effects of Terminal Motif on the Self-Assembly of Dexamethasone Derivatives

Effects of Terminal Motif on the Self-Assembly of Dexamethasone Derivatives

Tailoring the terminal motif of molecules including drugs might significantly affect their self-assembly tendency in aqueous solution, thus providing a rational strategy to modulate its macroscopic characteristics of supramolecular assembly. A model drug of dexamethasone (Dex) was esterified by diff...

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Bibliographic Details
Main Authors: Hui Liu, Ailing Yu, Mali Dai, Dan Lin, Deqing Lin, Xu Xu, Xingyi Li, Yuqin Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Chemistry
Subjects:
dexamethasone
self-assembly
terminal motif
drug delivery
hydrogel
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2020.00009/full

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