Monitoring And Managing Depression In Adolescents With Epilepsy: Current Perspectives
Giangennaro Coppola,1 Francesca Felicia Operto,1 Sara Matricardi,2 Alberto Verrotti3 1Child and Adolescent Neuropsychiatry, Department of Medicine, Surgery, and Odontoiatry, University of Salerno, Salerno, Italy; 2Department of Pediatric Neurology, Ospedali Riuniti, Ancona, Italy; 3Department of Ped...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2019-09-01
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| Series: | Neuropsychiatric Disease and Treatment |
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| Online Access: | https://www.dovepress.com/monitoring-and-managing-depression-in-adolescents-with-epilepsy-curren-peer-reviewed-article-NDT |
| _version_ | 1818997141128871936 |
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| author | Coppola G Operto FF Matricardi S Verrotti A |
| author_facet | Coppola G Operto FF Matricardi S Verrotti A |
| author_sort | Coppola G |
| collection | DOAJ |
| description | Giangennaro Coppola,1 Francesca Felicia Operto,1 Sara Matricardi,2 Alberto Verrotti3 1Child and Adolescent Neuropsychiatry, Department of Medicine, Surgery, and Odontoiatry, University of Salerno, Salerno, Italy; 2Department of Pediatric Neurology, Ospedali Riuniti, Ancona, Italy; 3Department of Pediatrics, University of L’Aquila, L’Aquila, ItalyCorrespondence: Giangennaro CoppolaChild and Adolescent Neuropsychiatry, Department of Medicine, Surgery and Odontoiatry, University of Salerno, Largo d’Ippocrate, 1, Salerno 84100, ItalyTel/Fax +39 089672578Email gcoppola@unisa.itAbstract: Epilepsy is associated with a significantly increased risk of developing depressive disorder during adolescence. On the other hand, depression is highly detected in adolescents with epilepsy. These findings highlight the importance of early identification and proper management of comorbid depression in adolescent age. The prevalence of depressive disorders in adolescents with epilepsy ranges between 8 and 35% and is higher than the general population of the same age. The relationship between epilepsy and depression is complex and potentially bidirectional, thereby suggesting a common underlying pathophysiology. Furthermore, failure to detect and treat depressive disorder mostly in adolescence could lead to several negative implications such as an increased risk of suicidal ideation or behavior and poor quality of life. A number of methods are available to detect depressive disorder, such as psychiatric or psychological assessments, structured or semi-structured interviews, and self-report screening tools. Thus, physicians should be able to regularly screen depressive symptoms in youths with epilepsy. Recently, the NDDI-E-.Y inventory has been developed from the adult NDDI-E, and has been validated in many countries. NDDI-E-Y has showed reliable validity, being a brief screening tool (12 items) that can be easily included in routine epilepsy care. The first step to be considered for the management of depressive disorder in adolescents with epilepsy is to consider potential reversible causes of anxiety and depression (i.e., a new AEDs; seizure control). Secondly, great attention has to be given to the education of the child/adolescent and his/her family, trying to improve knowledge about epilepsy as well as to decrease parental stress and improving the child’s sense of competence. Pharmacological treatment should also be considered in adolescents diagnosed with depression.Keywords: depression, adolescents, monitoring, management, epilepsy |
| first_indexed | 2024-12-20T21:40:55Z |
| format | Article |
| id | doaj.art-1400996ba2944419869ff998fdf7e1c6 |
| institution | Directory Open Access Journal |
| issn | 1178-2021 |
| language | English |
| last_indexed | 2024-12-20T21:40:55Z |
| publishDate | 2019-09-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Neuropsychiatric Disease and Treatment |
| spelling | doaj.art-1400996ba2944419869ff998fdf7e1c62022-12-21T19:25:47ZengDove Medical PressNeuropsychiatric Disease and Treatment1178-20212019-09-01Volume 152773278048787Monitoring And Managing Depression In Adolescents With Epilepsy: Current PerspectivesCoppola GOperto FFMatricardi SVerrotti AGiangennaro Coppola,1 Francesca Felicia Operto,1 Sara Matricardi,2 Alberto Verrotti3 1Child and Adolescent Neuropsychiatry, Department of Medicine, Surgery, and Odontoiatry, University of Salerno, Salerno, Italy; 2Department of Pediatric Neurology, Ospedali Riuniti, Ancona, Italy; 3Department of Pediatrics, University of L’Aquila, L’Aquila, ItalyCorrespondence: Giangennaro CoppolaChild and Adolescent Neuropsychiatry, Department of Medicine, Surgery and Odontoiatry, University of Salerno, Largo d’Ippocrate, 1, Salerno 84100, ItalyTel/Fax +39 089672578Email gcoppola@unisa.itAbstract: Epilepsy is associated with a significantly increased risk of developing depressive disorder during adolescence. On the other hand, depression is highly detected in adolescents with epilepsy. These findings highlight the importance of early identification and proper management of comorbid depression in adolescent age. The prevalence of depressive disorders in adolescents with epilepsy ranges between 8 and 35% and is higher than the general population of the same age. The relationship between epilepsy and depression is complex and potentially bidirectional, thereby suggesting a common underlying pathophysiology. Furthermore, failure to detect and treat depressive disorder mostly in adolescence could lead to several negative implications such as an increased risk of suicidal ideation or behavior and poor quality of life. A number of methods are available to detect depressive disorder, such as psychiatric or psychological assessments, structured or semi-structured interviews, and self-report screening tools. Thus, physicians should be able to regularly screen depressive symptoms in youths with epilepsy. Recently, the NDDI-E-.Y inventory has been developed from the adult NDDI-E, and has been validated in many countries. NDDI-E-Y has showed reliable validity, being a brief screening tool (12 items) that can be easily included in routine epilepsy care. The first step to be considered for the management of depressive disorder in adolescents with epilepsy is to consider potential reversible causes of anxiety and depression (i.e., a new AEDs; seizure control). Secondly, great attention has to be given to the education of the child/adolescent and his/her family, trying to improve knowledge about epilepsy as well as to decrease parental stress and improving the child’s sense of competence. Pharmacological treatment should also be considered in adolescents diagnosed with depression.Keywords: depression, adolescents, monitoring, management, epilepsyhttps://www.dovepress.com/monitoring-and-managing-depression-in-adolescents-with-epilepsy-curren-peer-reviewed-article-NDTdepressionadolescentsmonitoringmanagementepilepsy |
| spellingShingle | Coppola G Operto FF Matricardi S Verrotti A Monitoring And Managing Depression In Adolescents With Epilepsy: Current Perspectives Neuropsychiatric Disease and Treatment depression adolescents monitoring management epilepsy |
| title | Monitoring And Managing Depression In Adolescents With Epilepsy: Current Perspectives |
| title_full | Monitoring And Managing Depression In Adolescents With Epilepsy: Current Perspectives |
| title_fullStr | Monitoring And Managing Depression In Adolescents With Epilepsy: Current Perspectives |
| title_full_unstemmed | Monitoring And Managing Depression In Adolescents With Epilepsy: Current Perspectives |
| title_short | Monitoring And Managing Depression In Adolescents With Epilepsy: Current Perspectives |
| title_sort | monitoring and managing depression in adolescents with epilepsy current perspectives |
| topic | depression adolescents monitoring management epilepsy |
| url | https://www.dovepress.com/monitoring-and-managing-depression-in-adolescents-with-epilepsy-curren-peer-reviewed-article-NDT |
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