Effect of buccal fat autotransplantation on improving the alveolar socket bone regeneration: An in-vivo study
Background: There are various materials used for socket preservation following dental extraction. The aim of the present animal study was to histologically investigate the efficacy of buccal fat autotransplantation on alveolar bone regeneration following dental extraction. Study design: In this pros...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-03-01
|
| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024041628 |
| _version_ | 1797224108263473152 |
|---|---|
| author | Iman Mohammadi Amir Najafi Sayed Mohammad Razavi Saber Khazaei Golnaz Tajmiri |
| author_facet | Iman Mohammadi Amir Najafi Sayed Mohammad Razavi Saber Khazaei Golnaz Tajmiri |
| author_sort | Iman Mohammadi |
| collection | DOAJ |
| description | Background: There are various materials used for socket preservation following dental extraction. The aim of the present animal study was to histologically investigate the efficacy of buccal fat autotransplantation on alveolar bone regeneration following dental extraction. Study design: In this prospective, double-blind laboratory experiment with a split-mouth design, 16 mandibular second premolar teeth in eight beagle dogs were extracted, and half of the extraction sockets were randomly filled using buccal fat autotransplantation. Other samples were left untouched to heal normally by the formed blood clot. Buccal fat autotransplantation was the primary predictor variable, and the type and amount of newly formed bone were the primary outcome variables. Assessment methods were the H & E coloring technique and histomorphometric evaluation. The significance level was set at 0.05, and data was subjected to Chi-Square and Wilcoxon signed-rank tests using SAS statistical software version 9.4. Results: From the total number of 16 samples in 8 dogs, 50% of the samples in the intervention group represented inflammation with lower intensity compared to 33% in the control group; however, this difference was not considered statistically significant (Chi-Square test, P-value = 0.55). Wilcoxon test results showed no statistically significant difference between the two groups regarding the mean amount of total bone formation (Z = 0.00, P-value = 1.00). Conclusion: It was inferred from the outcomes of the present study that when compared to the normal healing of the socket, buccal fat autotransplantation did not represent with superior outcome concerning the socket bone regeneration. |
| first_indexed | 2024-04-24T13:47:52Z |
| format | Article |
| id | doaj.art-1405880fd51b4dcda16a1d49c8614a1c |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-24T13:47:52Z |
| publishDate | 2024-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-1405880fd51b4dcda16a1d49c8614a1c2024-04-04T05:06:54ZengElsevierHeliyon2405-84402024-03-01106e28131Effect of buccal fat autotransplantation on improving the alveolar socket bone regeneration: An in-vivo studyIman Mohammadi0Amir Najafi1Sayed Mohammad Razavi2Saber Khazaei3Golnaz Tajmiri4Department of Oral and Maxillofacial Surgery, Dental Implants Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, IranOral and Maxillofacial Surgery Department, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, IranDepartment of Oral and Maxillofacial Pathology, Dental Implants Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, IranDepartment of Endodontics, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, IranDental Implants Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran; Corresponding author. Dental Implants Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Hezar-jerib St., Isfahan, 8174673461, Iran.Background: There are various materials used for socket preservation following dental extraction. The aim of the present animal study was to histologically investigate the efficacy of buccal fat autotransplantation on alveolar bone regeneration following dental extraction. Study design: In this prospective, double-blind laboratory experiment with a split-mouth design, 16 mandibular second premolar teeth in eight beagle dogs were extracted, and half of the extraction sockets were randomly filled using buccal fat autotransplantation. Other samples were left untouched to heal normally by the formed blood clot. Buccal fat autotransplantation was the primary predictor variable, and the type and amount of newly formed bone were the primary outcome variables. Assessment methods were the H & E coloring technique and histomorphometric evaluation. The significance level was set at 0.05, and data was subjected to Chi-Square and Wilcoxon signed-rank tests using SAS statistical software version 9.4. Results: From the total number of 16 samples in 8 dogs, 50% of the samples in the intervention group represented inflammation with lower intensity compared to 33% in the control group; however, this difference was not considered statistically significant (Chi-Square test, P-value = 0.55). Wilcoxon test results showed no statistically significant difference between the two groups regarding the mean amount of total bone formation (Z = 0.00, P-value = 1.00). Conclusion: It was inferred from the outcomes of the present study that when compared to the normal healing of the socket, buccal fat autotransplantation did not represent with superior outcome concerning the socket bone regeneration.http://www.sciencedirect.com/science/article/pii/S2405844024041628Alveolar processTooth socketAdipose tissueBone regenerationTooth extraction |
| spellingShingle | Iman Mohammadi Amir Najafi Sayed Mohammad Razavi Saber Khazaei Golnaz Tajmiri Effect of buccal fat autotransplantation on improving the alveolar socket bone regeneration: An in-vivo study Heliyon Alveolar process Tooth socket Adipose tissue Bone regeneration Tooth extraction |
| title | Effect of buccal fat autotransplantation on improving the alveolar socket bone regeneration: An in-vivo study |
| title_full | Effect of buccal fat autotransplantation on improving the alveolar socket bone regeneration: An in-vivo study |
| title_fullStr | Effect of buccal fat autotransplantation on improving the alveolar socket bone regeneration: An in-vivo study |
| title_full_unstemmed | Effect of buccal fat autotransplantation on improving the alveolar socket bone regeneration: An in-vivo study |
| title_short | Effect of buccal fat autotransplantation on improving the alveolar socket bone regeneration: An in-vivo study |
| title_sort | effect of buccal fat autotransplantation on improving the alveolar socket bone regeneration an in vivo study |
| topic | Alveolar process Tooth socket Adipose tissue Bone regeneration Tooth extraction |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024041628 |
| work_keys_str_mv | AT imanmohammadi effectofbuccalfatautotransplantationonimprovingthealveolarsocketboneregenerationaninvivostudy AT amirnajafi effectofbuccalfatautotransplantationonimprovingthealveolarsocketboneregenerationaninvivostudy AT sayedmohammadrazavi effectofbuccalfatautotransplantationonimprovingthealveolarsocketboneregenerationaninvivostudy AT saberkhazaei effectofbuccalfatautotransplantationonimprovingthealveolarsocketboneregenerationaninvivostudy AT golnaztajmiri effectofbuccalfatautotransplantationonimprovingthealveolarsocketboneregenerationaninvivostudy |