Cancer co-opts differentiation of B-cell precursors into macrophage-like cells
The tumour microenvironment has been shown to change the phenotypes and functionality of immune cells to enable tumour propagation. Here authors show that cancers can derail B cell development to give rise to macrophage-like cells, contributing to cancer progression and metastasis via disabling loca...
Main Authors: | Chen Chen, Bongsoo Park, Emeline Ragonnaud, Monica Bodogai, Xin Wang, Le Zong, Jung-Min Lee, Isabel Beerman, Arya Biragyn |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-09-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-33117-y |
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