Dexmedetomidine versus propofol for sedation in patients undergoing vitreoretinal surgery under sub-Tenon′s anesthesia
Purpose: The purpose of this study was to evaluate the hemodynamic, respiratory effects, the recovery profile, surgeons, and patients satisfaction with dexmedetomidine sedation compared with those of propofol sedation in patients undergoing vitreoretinal surgery under sub-Tenon′s anesthesia. Methods...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2011-01-01
|
| Series: | Saudi Journal of Anaesthesia |
| Subjects: | |
| Online Access: | http://www.saudija.org/article.asp?issn=1658-354X;year=2011;volume=5;issue=1;spage=36;epage=41;aulast=Ghali |
| _version_ | 1818110896368517120 |
|---|---|
| author | Ashraf Ghali Abdul Kader Mahfouz Tapio Ihanamäki Ashraf M. El Btarny |
| author_facet | Ashraf Ghali Abdul Kader Mahfouz Tapio Ihanamäki Ashraf M. El Btarny |
| author_sort | Ashraf Ghali |
| collection | DOAJ |
| description | Purpose: The purpose of this study was to evaluate the hemodynamic, respiratory effects, the recovery profile, surgeons, and patients satisfaction with dexmedetomidine sedation compared with those of propofol sedation in patients undergoing vitreoretinal surgery under sub-Tenon′s anesthesia. Methods: Sixty patients were enrolled in this prospective, single-blind, randomized study. The patients were divided into two groups to receive either dexmedetomidine (group D) or propofol (group P). Sedation level was titrated to a Ramsay sedation scale (RSS) of 3. Hemodynamic and respiratory effects, postoperative recovery time, analgesic effects, surgeons and patients satisfaction were assessed. Results: Both groups provided a similar significant reduction in heart rate and mean arterial pressure compared with baseline values. The respiratory rate values of the dexmedetomidine group were significantly higher than those in the propofol group. The oxygen saturation values of the dexmedetomidine group were significantly higher than those of the propofol group. The expired CO 2 was similar in both groups. Postoperatively, the time to achieve an Aldrete score of 10 was similar in both groups. Dexmedetomidine patients have significantly lower visual analog scale for pain than propofol patients. The surgeon satisfaction with patients′ sedation was similar for both groups. The patients′ satisfaction was higher in the dexmedetomidine group. Conclusion: Dexmedetomidine at similar sedation levels with propofol was associated with equivalent hemodynamic effects, maintaining an adequate respiratory function, similar time of discharge from PACU, better analgesic properties, similar surgeon′s satisfaction, and higher patient′s satisfaction. Thus, dexmedetomidine may prove to be a valuable adjuvant for sedation in patients undergoing vitreoretinal surgery under sub-Tenon′s anesthesia. |
| first_indexed | 2024-12-11T02:54:26Z |
| format | Article |
| id | doaj.art-1408960627ba4f39bbe4a91fb75f9a6c |
| institution | Directory Open Access Journal |
| issn | 1658-354X |
| language | English |
| last_indexed | 2024-12-11T02:54:26Z |
| publishDate | 2011-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Saudi Journal of Anaesthesia |
| spelling | doaj.art-1408960627ba4f39bbe4a91fb75f9a6c2022-12-22T01:23:12ZengWolters Kluwer Medknow PublicationsSaudi Journal of Anaesthesia1658-354X2011-01-0151364110.4103/1658-354X.76506Dexmedetomidine versus propofol for sedation in patients undergoing vitreoretinal surgery under sub-Tenon′s anesthesiaAshraf GhaliAbdul Kader MahfouzTapio IhanamäkiAshraf M. El BtarnyPurpose: The purpose of this study was to evaluate the hemodynamic, respiratory effects, the recovery profile, surgeons, and patients satisfaction with dexmedetomidine sedation compared with those of propofol sedation in patients undergoing vitreoretinal surgery under sub-Tenon′s anesthesia. Methods: Sixty patients were enrolled in this prospective, single-blind, randomized study. The patients were divided into two groups to receive either dexmedetomidine (group D) or propofol (group P). Sedation level was titrated to a Ramsay sedation scale (RSS) of 3. Hemodynamic and respiratory effects, postoperative recovery time, analgesic effects, surgeons and patients satisfaction were assessed. Results: Both groups provided a similar significant reduction in heart rate and mean arterial pressure compared with baseline values. The respiratory rate values of the dexmedetomidine group were significantly higher than those in the propofol group. The oxygen saturation values of the dexmedetomidine group were significantly higher than those of the propofol group. The expired CO 2 was similar in both groups. Postoperatively, the time to achieve an Aldrete score of 10 was similar in both groups. Dexmedetomidine patients have significantly lower visual analog scale for pain than propofol patients. The surgeon satisfaction with patients′ sedation was similar for both groups. The patients′ satisfaction was higher in the dexmedetomidine group. Conclusion: Dexmedetomidine at similar sedation levels with propofol was associated with equivalent hemodynamic effects, maintaining an adequate respiratory function, similar time of discharge from PACU, better analgesic properties, similar surgeon′s satisfaction, and higher patient′s satisfaction. Thus, dexmedetomidine may prove to be a valuable adjuvant for sedation in patients undergoing vitreoretinal surgery under sub-Tenon′s anesthesia.http://www.saudija.org/article.asp?issn=1658-354X;year=2011;volume=5;issue=1;spage=36;epage=41;aulast=GhaliDexmedetomidinepropofolsedationvitreoretinal surgery |
| spellingShingle | Ashraf Ghali Abdul Kader Mahfouz Tapio Ihanamäki Ashraf M. El Btarny Dexmedetomidine versus propofol for sedation in patients undergoing vitreoretinal surgery under sub-Tenon′s anesthesia Saudi Journal of Anaesthesia Dexmedetomidine propofol sedation vitreoretinal surgery |
| title | Dexmedetomidine versus propofol for sedation in patients undergoing vitreoretinal surgery under sub-Tenon′s anesthesia |
| title_full | Dexmedetomidine versus propofol for sedation in patients undergoing vitreoretinal surgery under sub-Tenon′s anesthesia |
| title_fullStr | Dexmedetomidine versus propofol for sedation in patients undergoing vitreoretinal surgery under sub-Tenon′s anesthesia |
| title_full_unstemmed | Dexmedetomidine versus propofol for sedation in patients undergoing vitreoretinal surgery under sub-Tenon′s anesthesia |
| title_short | Dexmedetomidine versus propofol for sedation in patients undergoing vitreoretinal surgery under sub-Tenon′s anesthesia |
| title_sort | dexmedetomidine versus propofol for sedation in patients undergoing vitreoretinal surgery under sub tenon s anesthesia |
| topic | Dexmedetomidine propofol sedation vitreoretinal surgery |
| url | http://www.saudija.org/article.asp?issn=1658-354X;year=2011;volume=5;issue=1;spage=36;epage=41;aulast=Ghali |
| work_keys_str_mv | AT ashrafghali dexmedetomidineversuspropofolforsedationinpatientsundergoingvitreoretinalsurgeryundersubtenonsanesthesia AT abdulkadermahfouz dexmedetomidineversuspropofolforsedationinpatientsundergoingvitreoretinalsurgeryundersubtenonsanesthesia AT tapioihanamaki dexmedetomidineversuspropofolforsedationinpatientsundergoingvitreoretinalsurgeryundersubtenonsanesthesia AT ashrafmelbtarny dexmedetomidineversuspropofolforsedationinpatientsundergoingvitreoretinalsurgeryundersubtenonsanesthesia |