Euchromatin islands in large heterochromatin domains are enriched for CTCF binding and differentially DNA-methylated regions

Euchromatin islands in large heterochromatin domains are enriched for CTCF binding and differentially DNA-methylated regions

<p>Abstract</p> <p>Background</p> <p>The organization of higher order chromatin is an emerging epigenetic mechanism for understanding development and disease. We and others have previously observed dynamic changes during differentiation and oncogenesis in large heteroch...

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Bibliographic Details
Main Authors: Wen Bo, Wu Hao, Loh Yuin-Han, Briem Eirikur, Daley George Q, Feinberg Andrew P
Format: Article
Language:English
Published: BMC 2012-10-01
Series:BMC Genomics
Subjects:
Epigenetics
H3K9me2
Euchromatin islands
CTCF
DNA methylation
Online Access:http://www.biomedcentral.com/1471-2164/13/566

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