Gymnotic uptake of AntimiRs alter microRNA-34a levels in 2D and 3D epithelial cell culture

Gymnotic uptake of AntimiRs alter microRNA-34a levels in 2D and 3D epithelial cell culture

MicroRNAs are attractive therapeutic targets in many diseases, including chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis. Among microRNA inhibitors antimiRs have been proven successful in lowering aberrant microRNA levels in the clinic. We present a set of antimiRs targeting...

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Bibliographic Details
Main Authors: Julie Weidner, Ewa Kolosionek, Reetta Holmila, Elisabeth Ax, Marion Garreau, Felix Gnerlich, Henric Olsson, Werngard Czechtizky, Stefan Vollmer, Anna M. Rydzik
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MT: Oligonucleotides: Therapies and Applications
miRNA
antimiRs
AMO
miR-34a
therapeutic oligonucleotides
Online Access:http://www.sciencedirect.com/science/article/pii/S216225312300224X

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