Circulating exosomes and gut microbiome induced insulin resistance in mice exposed to intermittent hypoxia: Effects of physical activity

Circulating exosomes and gut microbiome induced insulin resistance in mice exposed to intermittent hypoxia: Effects of physical activity

Background: Gut microbiota (GM) contribute to obesity and insulin resistance (IR). Obstructive sleep apnea (OSA), characterized by intermittent hypoxia (IH), promotes IR and alters GM. Since circulating exosomes are implicated in IR, we examined the effects of IH and physical activity (PA) in mice o...

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Bibliographic Details
Main Authors: Abdelnaby Khalyfa, Aaron Ericsson, Zhuanghong Qiao, Isaac Almendros, Ramon Farré, David Gozal
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:EBioMedicine
Subjects:
Intermittent hypoxia
Exercise
Physical activity
Gut microbiome
Metabolome
OSA
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421000013

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