Predictive models of efficacy and public health impact of vaccination with rotavirus vaccine in Ukraine

There were presented the results of the computational and theoretical studies related to assessing of an efficacy and public health impact of a vaccination with a rotavirus vaccine in Ukraine. The required indicators are: the genotype-specific vaccine efficacy, number of the severe illness preventio...

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Bibliographic Details
Main Authors: Sergey Alexandrovich Solovyov, Johnie . Rose, Iryna Vladimirovna Dzyublyk, Elena Petrovna Trokhimenko
Format: Article
Language:Russian
Published: Institute of Computer Science 2012-06-01
Series:Компьютерные исследования и моделирование
Subjects:
Online Access:http://crm.ics.org.ru/uploads/crmissues/crm_2012_2/12215.pdf
Description
Summary:There were presented the results of the computational and theoretical studies related to assessing of an efficacy and public health impact of a vaccination with a rotavirus vaccine in Ukraine. The required indicators are: the genotype-specific vaccine efficacy, number of the severe illness preventions, hospitalizations, outpatient visits and deaths. The results were obtained in a form of tree of decisions based on Makrov model by using mathematical model with computer simulation. The results showed the significant positive effect of the vaccination compared to no vaccination, in case of high level of vaccine coverage in Ukraine.
ISSN:2076-7633
2077-6853