The Effectiveness of Intra-Articular Injection of Hypertonic Saline in Pain Control and Function of Patients with Knee Osteoarthritis
Background: To report the effectiveness of intra-articular injection of hypertonic saline in pain reduction and function improvement of patients with knee osteoarthritis. Methods: Patients with knee pain and dysfunction who fulfilled the American College of Rheumatology criteria and whose illness wa...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2020-07-01
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| Series: | Journal of Orthopedic and Spine Trauma |
| Subjects: | |
| Online Access: | https://jost.tums.ac.ir/index.php/jost/article/view/161 |
| _version_ | 1818890599913226240 |
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| author | Behrouz Tavana Sirous Azizi Sharif Najafi Ensie Taftian Nastaran Maghbouli |
| author_facet | Behrouz Tavana Sirous Azizi Sharif Najafi Ensie Taftian Nastaran Maghbouli |
| author_sort | Behrouz Tavana |
| collection | DOAJ |
| description | Background: To report the effectiveness of intra-articular injection of hypertonic saline in pain reduction and function improvement of patients with knee osteoarthritis.
Methods: Patients with knee pain and dysfunction who fulfilled the American College of Rheumatology criteria and whose illness was sub-acute or chronic were enrolled. We performed a single Intra-articular injection of 5cc of hypertonic saline solution 5%. Measured outcomes were Visual Analogue Scale (VAS) score and Knee injury and osteoarthritis outcome score (KOOS) evaluated before and 1 month after intervention.
Results: a total of 28 patients with mean age of 66.3 years were surveyed. Overall, study participants reported clinically and statistically significant reduction in VAS and KOOS subscales for symptoms, pain, function, daily living, sports, recreational activities and quality of life in one month of follow-up with respect to the patients’ mean baseline scores which were reduced by 24.47%, 42.74%, 54.96%, 43.78% and 63.63%, respectively (P-value<0.05 for all comparisons). Although obese patients (BMI≥30 kg/m2) showed less improvement in terms of pain, sports and quality of life subscales of KOOS subscales, compared with non-obese patients (BMI<30 kg/m2), VAS scale difference was not significant.
Conclusions: Intra-articular injection of hypertonic saline yields a statistically and clinically significant short-term pain reduction and functional improvement of patients with knee osteoarthritis. |
| first_indexed | 2024-12-19T17:27:29Z |
| format | Article |
| id | doaj.art-141575a151d84212bca10b754ae6406b |
| institution | Directory Open Access Journal |
| issn | 2538-2330 2538-4600 |
| language | English |
| last_indexed | 2024-12-19T17:27:29Z |
| publishDate | 2020-07-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Journal of Orthopedic and Spine Trauma |
| spelling | doaj.art-141575a151d84212bca10b754ae6406b2022-12-21T20:12:31ZengTehran University of Medical SciencesJournal of Orthopedic and Spine Trauma2538-23302538-46002020-07-015110.18502/jost.v5i1.3320The Effectiveness of Intra-Articular Injection of Hypertonic Saline in Pain Control and Function of Patients with Knee OsteoarthritisBehrouz Tavana0Sirous Azizi1Sharif Najafi2Ensie Taftian3Nastaran Maghbouli4AJA UnivAssistant Professor, Department of Physical Medicine and Rehabilitation, School of Medicine, AJA University of Medical Sciences, Tehran, Iranersity of Medical SciencesAssistant Professor, Department of Physical Medicine and Rehabilitation, School of Medicine, AJA University of Medical Sciences, Tehran, IranAssistant Professor, Department of Physical Medicine and Rehabilitation, School of Medicine, AJA University of Medical Sciences, Tehran, IranClinical Resident, Department of Physical Medicine and Rehabilitation, School of Medicine, AJA University of Medical Sciences, Tehran, IranClinical Resident, Department of Physical Medicine and Rehabilitation, Imam Khomeini Hospital Complex, School of Medicine, Tehran University of Medical Sciences, Tehran, IranBackground: To report the effectiveness of intra-articular injection of hypertonic saline in pain reduction and function improvement of patients with knee osteoarthritis. Methods: Patients with knee pain and dysfunction who fulfilled the American College of Rheumatology criteria and whose illness was sub-acute or chronic were enrolled. We performed a single Intra-articular injection of 5cc of hypertonic saline solution 5%. Measured outcomes were Visual Analogue Scale (VAS) score and Knee injury and osteoarthritis outcome score (KOOS) evaluated before and 1 month after intervention. Results: a total of 28 patients with mean age of 66.3 years were surveyed. Overall, study participants reported clinically and statistically significant reduction in VAS and KOOS subscales for symptoms, pain, function, daily living, sports, recreational activities and quality of life in one month of follow-up with respect to the patients’ mean baseline scores which were reduced by 24.47%, 42.74%, 54.96%, 43.78% and 63.63%, respectively (P-value<0.05 for all comparisons). Although obese patients (BMI≥30 kg/m2) showed less improvement in terms of pain, sports and quality of life subscales of KOOS subscales, compared with non-obese patients (BMI<30 kg/m2), VAS scale difference was not significant. Conclusions: Intra-articular injection of hypertonic saline yields a statistically and clinically significant short-term pain reduction and functional improvement of patients with knee osteoarthritis.https://jost.tums.ac.ir/index.php/jost/article/view/161Knee; Osteoarthritis; Injections; Intra-Articular Injections |
| spellingShingle | Behrouz Tavana Sirous Azizi Sharif Najafi Ensie Taftian Nastaran Maghbouli The Effectiveness of Intra-Articular Injection of Hypertonic Saline in Pain Control and Function of Patients with Knee Osteoarthritis Journal of Orthopedic and Spine Trauma Knee; Osteoarthritis; Injections; Intra-Articular Injections |
| title | The Effectiveness of Intra-Articular Injection of Hypertonic Saline in Pain Control and Function of Patients with Knee Osteoarthritis |
| title_full | The Effectiveness of Intra-Articular Injection of Hypertonic Saline in Pain Control and Function of Patients with Knee Osteoarthritis |
| title_fullStr | The Effectiveness of Intra-Articular Injection of Hypertonic Saline in Pain Control and Function of Patients with Knee Osteoarthritis |
| title_full_unstemmed | The Effectiveness of Intra-Articular Injection of Hypertonic Saline in Pain Control and Function of Patients with Knee Osteoarthritis |
| title_short | The Effectiveness of Intra-Articular Injection of Hypertonic Saline in Pain Control and Function of Patients with Knee Osteoarthritis |
| title_sort | effectiveness of intra articular injection of hypertonic saline in pain control and function of patients with knee osteoarthritis |
| topic | Knee; Osteoarthritis; Injections; Intra-Articular Injections |
| url | https://jost.tums.ac.ir/index.php/jost/article/view/161 |
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