The major role of Listeria monocytogenes folic acid metabolism during infection is the generation of N-formylmethionine
ABSTRACT Folic acid and its derivatives (folates) play central roles in one-carbon metabolism, necessary for the synthesis of purines, pyrimidines, and some amino acids. Antifolate drugs are widely used as broad-spectrum antibiotics for bacterial infections, including listeriosis, a disease caused b...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2023-10-01
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| Series: | mBio |
| Subjects: | |
| Online Access: | https://journals.asm.org/doi/10.1128/mbio.01074-23 |