The Role of the Stroma in Carcinogenesis
This systematic review considers the most recent attitudes and news regarding the influence of the stroma on tumor initiation and progression. It is now widely accepted that tumor stroma plays an active role in carcinogenesis. Many different signaling molecules, ligands and signaling pathways recen...
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Format: | Article |
Language: | English |
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Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2006-02-01
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Series: | Biomolecules & Biomedicine |
Subjects: | |
Online Access: | https://www.bjbms.org/ojs/index.php/bjbms/article/view/3207 |
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author | Nurija Bilalović Semir Vranić Fadila Serdarević Faris Fočo |
author_facet | Nurija Bilalović Semir Vranić Fadila Serdarević Faris Fočo |
author_sort | Nurija Bilalović |
collection | DOAJ |
description |
This systematic review considers the most recent attitudes and news regarding the influence of the stroma on tumor initiation and progression. It is now widely accepted that tumor stroma plays an active role in carcinogenesis. Many different signaling molecules, ligands and signaling pathways recently have been discovered. This review considers the complexity of interactions between malignant cells and its stroma (cross-talk). The recent advances and better understanding of the tumor-stroma interactions will have important impact on the new and combined therapeutic approaches and modalities.
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first_indexed | 2024-04-24T23:31:09Z |
format | Article |
id | doaj.art-141e26882cd94fe59d297c9b8464b6d6 |
institution | Directory Open Access Journal |
issn | 2831-0896 2831-090X |
language | English |
last_indexed | 2024-04-24T23:31:09Z |
publishDate | 2006-02-01 |
publisher | Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina |
record_format | Article |
series | Biomolecules & Biomedicine |
spelling | doaj.art-141e26882cd94fe59d297c9b8464b6d62024-03-15T14:42:24ZengAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaBiomolecules & Biomedicine2831-08962831-090X2006-02-016110.17305/bjbms.2006.3207728The Role of the Stroma in CarcinogenesisNurija Bilalović0Semir Vranić1Fadila Serdarević2Faris Fočo3Department of Clinical Pathology and Cytology, Clinical Center of the University of SarajevoClinical Center of the University of SarajevoUniversity of South FloridaDepartment of Maxillofacial Surgery, Clinical Center of the University of Sarajevo This systematic review considers the most recent attitudes and news regarding the influence of the stroma on tumor initiation and progression. It is now widely accepted that tumor stroma plays an active role in carcinogenesis. Many different signaling molecules, ligands and signaling pathways recently have been discovered. This review considers the complexity of interactions between malignant cells and its stroma (cross-talk). The recent advances and better understanding of the tumor-stroma interactions will have important impact on the new and combined therapeutic approaches and modalities. https://www.bjbms.org/ojs/index.php/bjbms/article/view/3207carcinogenesistumor stromacross-talkstromal fibroblasts |
spellingShingle | Nurija Bilalović Semir Vranić Fadila Serdarević Faris Fočo The Role of the Stroma in Carcinogenesis Biomolecules & Biomedicine carcinogenesis tumor stroma cross-talk stromal fibroblasts |
title | The Role of the Stroma in Carcinogenesis |
title_full | The Role of the Stroma in Carcinogenesis |
title_fullStr | The Role of the Stroma in Carcinogenesis |
title_full_unstemmed | The Role of the Stroma in Carcinogenesis |
title_short | The Role of the Stroma in Carcinogenesis |
title_sort | role of the stroma in carcinogenesis |
topic | carcinogenesis tumor stroma cross-talk stromal fibroblasts |
url | https://www.bjbms.org/ojs/index.php/bjbms/article/view/3207 |
work_keys_str_mv | AT nurijabilalovic theroleofthestromaincarcinogenesis AT semirvranic theroleofthestromaincarcinogenesis AT fadilaserdarevic theroleofthestromaincarcinogenesis AT farisfoco theroleofthestromaincarcinogenesis AT nurijabilalovic roleofthestromaincarcinogenesis AT semirvranic roleofthestromaincarcinogenesis AT fadilaserdarevic roleofthestromaincarcinogenesis AT farisfoco roleofthestromaincarcinogenesis |