Decompressive craniectomy in traumatic brain injury Rationale and practice
Despite the growing fund of knowledge on the pathophysiology of traumatic brain injury, the outcomes of severe TBI remain abysmal. While the necrotic and apoptotic cascades triggered off by the primary traumatic insult remain refractory to treatment, the secondary sequelae of increased intracranial...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Thieme Medical and Scientific Publishers Pvt. Ltd.
2010-06-01
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| Series: | The Indian Journal of Neurotrauma |
| Subjects: | |
| Online Access: | http://www.ijntonline.com/June10/abstracts/03.PDF |
| _version_ | 1827614150968213504 |
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| author | Khalil I Mathai SM Sudumbrekar Shashi Vadhanan SK Sengupta TJ Rappai |
| author_facet | Khalil I Mathai SM Sudumbrekar Shashi Vadhanan SK Sengupta TJ Rappai |
| author_sort | Khalil I Mathai |
| collection | DOAJ |
| description | Despite the growing fund of knowledge on the pathophysiology of traumatic brain injury, the outcomes of severe TBI remain abysmal. While the necrotic and apoptotic cascades triggered off by the primary traumatic insult remain refractory to treatment, the secondary sequelae of increased intracranial pressure remain within the therapeutic realm. The benefit of evacuation of mass producing hematomas is beyond dispute. The management of brain edema however remains suboptimal despite the best medical management. The role of surgical evacuation of edema inducing contusions recalcitrant to osmotherapy is explored in this paper. The role of decompressive craniectomy in the control of refractory hypertension and the rationale and timing of the procedure are discussed |
| first_indexed | 2024-03-09T08:50:36Z |
| format | Article |
| id | doaj.art-141e4f50ddaa4825a317e396e65678d8 |
| institution | Directory Open Access Journal |
| issn | 0973-0508 |
| language | English |
| last_indexed | 2024-03-09T08:50:36Z |
| publishDate | 2010-06-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | The Indian Journal of Neurotrauma |
| spelling | doaj.art-141e4f50ddaa4825a317e396e65678d82023-12-02T14:13:40ZengThieme Medical and Scientific Publishers Pvt. Ltd.The Indian Journal of Neurotrauma0973-05082010-06-0171912Decompressive craniectomy in traumatic brain injury Rationale and practiceKhalil I MathaiSM SudumbrekarShashi VadhananSK SenguptaTJ RappaiDespite the growing fund of knowledge on the pathophysiology of traumatic brain injury, the outcomes of severe TBI remain abysmal. While the necrotic and apoptotic cascades triggered off by the primary traumatic insult remain refractory to treatment, the secondary sequelae of increased intracranial pressure remain within the therapeutic realm. The benefit of evacuation of mass producing hematomas is beyond dispute. The management of brain edema however remains suboptimal despite the best medical management. The role of surgical evacuation of edema inducing contusions recalcitrant to osmotherapy is explored in this paper. The role of decompressive craniectomy in the control of refractory hypertension and the rationale and timing of the procedure are discussedhttp://www.ijntonline.com/June10/abstracts/03.PDFbrain edemadecompressive craniectomy |
| spellingShingle | Khalil I Mathai SM Sudumbrekar Shashi Vadhanan SK Sengupta TJ Rappai Decompressive craniectomy in traumatic brain injury Rationale and practice The Indian Journal of Neurotrauma brain edema decompressive craniectomy |
| title | Decompressive craniectomy in traumatic brain injury Rationale and practice |
| title_full | Decompressive craniectomy in traumatic brain injury Rationale and practice |
| title_fullStr | Decompressive craniectomy in traumatic brain injury Rationale and practice |
| title_full_unstemmed | Decompressive craniectomy in traumatic brain injury Rationale and practice |
| title_short | Decompressive craniectomy in traumatic brain injury Rationale and practice |
| title_sort | decompressive craniectomy in traumatic brain injury rationale and practice |
| topic | brain edema decompressive craniectomy |
| url | http://www.ijntonline.com/June10/abstracts/03.PDF |
| work_keys_str_mv | AT khalilimathai decompressivecraniectomyintraumaticbraininjuryrationaleandpractice AT smsudumbrekar decompressivecraniectomyintraumaticbraininjuryrationaleandpractice AT shashivadhanan decompressivecraniectomyintraumaticbraininjuryrationaleandpractice AT sksengupta decompressivecraniectomyintraumaticbraininjuryrationaleandpractice AT tjrappai decompressivecraniectomyintraumaticbraininjuryrationaleandpractice |