Zebrafish as an experimental model for the simulation of neurological and craniofacial disorders

Zebrafish have gained momentum as a leading experimental model in recent years. At present, the zebrafish vertebrate model is increasingly used due to its multifactorial similarities to humans that include genetic, organ, and cellular factors. With the emergence of novel research techniques that are...

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Main Authors: Ashwin Rohan Rai, Teresa Joy, K. S. Rashmi, Rajalakshmi Rai, N. A. Vinodini, P. J. Jiji
Format: Article
Language:English
Published: Veterinary World 2022-01-01
Series:Veterinary World
Subjects:
Online Access:http://www.veterinaryworld.org/Vol.15/January-2022/4.pdf
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author Ashwin Rohan Rai
Teresa Joy
K. S. Rashmi
Rajalakshmi Rai
N. A. Vinodini
P. J. Jiji
author_facet Ashwin Rohan Rai
Teresa Joy
K. S. Rashmi
Rajalakshmi Rai
N. A. Vinodini
P. J. Jiji
author_sort Ashwin Rohan Rai
collection DOAJ
description Zebrafish have gained momentum as a leading experimental model in recent years. At present, the zebrafish vertebrate model is increasingly used due to its multifactorial similarities to humans that include genetic, organ, and cellular factors. With the emergence of novel research techniques that are very expensive, it is necessary to develop affordable and valid experimental models. This review aimed to highlight some of the most important similarities between zebrafish and humans by emphasizing the relevance of the first in simulating neurological disorders and craniofacial deformity.
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spelling doaj.art-14200a21813e40f193d92b8ab867fe5c2022-12-21T17:49:35ZengVeterinary WorldVeterinary World0972-89882231-09162022-01-01151222910.14202/vetworld.2022.22-29Zebrafish as an experimental model for the simulation of neurological and craniofacial disordersAshwin Rohan Rai0https://orcid.org/0000-0001-8574-1809Teresa Joy1https://orcid.org/0000-0003-1834-8606K. S. Rashmi2https://orcid.org/0000-0002-4603-1502Rajalakshmi Rai3https://orcid.org/0000-0003-0776-2254N. A. Vinodini4https://orcid.org/0000-0002-6277-7777P. J. Jiji5https://orcid.org/0000-0002-4925-4701Department of Anatomy, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.Department of Anatomy, American University of Antigua College of Medicine, University Park, Coolidge, St. John's, Antigua.Department of Physiology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.Department of Anatomy, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.Department of Physiology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.Department of Anatomy, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.Zebrafish have gained momentum as a leading experimental model in recent years. At present, the zebrafish vertebrate model is increasingly used due to its multifactorial similarities to humans that include genetic, organ, and cellular factors. With the emergence of novel research techniques that are very expensive, it is necessary to develop affordable and valid experimental models. This review aimed to highlight some of the most important similarities between zebrafish and humans by emphasizing the relevance of the first in simulating neurological disorders and craniofacial deformity.http://www.veterinaryworld.org/Vol.15/January-2022/4.pdfcraniofacial deformityexperimental modelneurological disorderszebrafish
spellingShingle Ashwin Rohan Rai
Teresa Joy
K. S. Rashmi
Rajalakshmi Rai
N. A. Vinodini
P. J. Jiji
Zebrafish as an experimental model for the simulation of neurological and craniofacial disorders
Veterinary World
craniofacial deformity
experimental model
neurological disorders
zebrafish
title Zebrafish as an experimental model for the simulation of neurological and craniofacial disorders
title_full Zebrafish as an experimental model for the simulation of neurological and craniofacial disorders
title_fullStr Zebrafish as an experimental model for the simulation of neurological and craniofacial disorders
title_full_unstemmed Zebrafish as an experimental model for the simulation of neurological and craniofacial disorders
title_short Zebrafish as an experimental model for the simulation of neurological and craniofacial disorders
title_sort zebrafish as an experimental model for the simulation of neurological and craniofacial disorders
topic craniofacial deformity
experimental model
neurological disorders
zebrafish
url http://www.veterinaryworld.org/Vol.15/January-2022/4.pdf
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AT ksrashmi zebrafishasanexperimentalmodelforthesimulationofneurologicalandcraniofacialdisorders
AT rajalakshmirai zebrafishasanexperimentalmodelforthesimulationofneurologicalandcraniofacialdisorders
AT navinodini zebrafishasanexperimentalmodelforthesimulationofneurologicalandcraniofacialdisorders
AT pjjiji zebrafishasanexperimentalmodelforthesimulationofneurologicalandcraniofacialdisorders