Mandarin Fish (Siniperca chuatsi) p53 Regulates Glutaminolysis Induced by Virus via the p53/miR145-5p/c-Myc Pathway in Chinese Perch Brain Cells

Mandarin Fish (Siniperca chuatsi) p53 Regulates Glutaminolysis Induced by Virus via the p53/miR145-5p/c-Myc Pathway in Chinese Perch Brain Cells

ABSTRACT p53, as an important tumor suppressor protein, has recently been implicated in host antiviral defense. The present study found that the expression of mandarin fish (Siniperca chuatsi) p53 (Sc-p53) was negatively associated with infectious spleen and kidney necrosis virus (ISKNV) and Siniper...

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Bibliographic Details
Main Authors: Caimei Ye, Shangui Liu, Ningqiu Li, Shaozhi Zuo, Yinjie Niu, Qiang Lin, Hongru Liang, Xia Luo, Xiaozhe Fu
Format: Article
Language:English
Published: American Society for Microbiology 2022-04-01
Series:Microbiology Spectrum
Subjects:
Siniperca chuatsi
Sc-p53
glutaminolysis
p53/miR145-5p/c-Myc
ISKNV
SCRV
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02727-21

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