Genetic Association of Pulmonary Surfactant Protein Genes, SFTPA1, SFTPA2, SFTPB, SFTPC, and SFTPD With Cystic Fibrosis

Genetic Association of Pulmonary Surfactant Protein Genes, SFTPA1, SFTPA2, SFTPB, SFTPC, and SFTPD With Cystic Fibrosis

Surfactant proteins (SP) are involved in surfactant function and innate immunity in the human lung. Both lung function and innate immunity are altered in CF, and altered SP levels and genetic association are observed in Cystic Fibrosis (CF). We hypothesized that single nucleotide polymorphisms (SNPs...

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Bibliographic Details
Main Authors: Zhenwu Lin, Nithyananda Thorenoor, Rongling Wu, Susan L. DiAngelo, Meixia Ye, Neal J. Thomas, Xiaojie Liao, Tony R. Lin, Stuart Warren, Joanna Floros
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
surfactant protein
SP-A
SP-B
SP-C
SP-D
cystic fibrosis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02256/full

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