SOME FEATURES OF CYTOKINE PROFILE IN SEVERE PYOINFLAMMATORY DISEASES OF FACE AND NECK

Abstract. This work presents immunological data of one-hundred patients with severe pyoinflammatory diseases of face and neck area. Upon laboratory evaluation of patients with such pathology, it was shown that production of IL-1β, IL-2, IL-6, IL-8, IL-10, Rа-IL-1β is induced in this cohort. A clinic...

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Bibliographic Details
Main Authors: L. M. Karzakova, I. A. Sidorov, A. N. Volkov, S. I. Kudrjashov
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2014-07-01
Series:Медицинская иммунология
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Online Access:https://www.mimmun.ru/mimmun/article/view/456
Description
Summary:Abstract. This work presents immunological data of one-hundred patients with severe pyoinflammatory diseases of face and neck area. Upon laboratory evaluation of patients with such pathology, it was shown that production of IL-1β, IL-2, IL-6, IL-8, IL-10, Rа-IL-1β is induced in this cohort. A clinically unfavorable pattern of cytokine profile was specified in patients with severe pyoinflammatory diseases of face and neck region. Its common feature is an imbalance in cytokine network associated with overproduction of immunosuppressive cytokines.
ISSN:1563-0625
2313-741X