Green Synthesis of Thiazolidine-2,4-dione Derivatives and Their Lipoxygenase Inhibition Activity With QSAR and Molecular Docking Studies

Green Synthesis of Thiazolidine-2,4-dione Derivatives and Their Lipoxygenase Inhibition Activity With QSAR and Molecular Docking Studies

Thiazolidinediones are five-membered, heterocyclic compounds that possess a number of pharmacological activities such as antihyperglycemic, antitumor, antiarthritic, anti-inflammatory, and antimicrobial. Conventional methods for their synthesis are often environmentally unacceptable due to the utili...

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Bibliographic Details
Main Authors: Melita Lončarić, Ivica Strelec, Valentina Pavić, Vesna Rastija, Maja Karnaš, Maja Molnar
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Chemistry
Subjects:
2,4-thiazolidinedione
synthesis
deep eutectic solvents
green chemistry
lipoxygenase
QSAR
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2022.912822/full

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