A stretchable hardness sensor for the assessment of skin disease in systemic sclerosis
Objective To determine the validity of a hardness sensor to objectively assess skin induration in patients with systemic sclerosis, and to compare the hardness sensor with the modified Rodnan skin score (MRSS) and a durometer.Methods The skin induration was measured in two assessments: a Latin squar...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2023-10-01
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| Series: | RMD Open |
| Online Access: | https://rmdopen.bmj.com/content/9/4/e003512.full |
| _version_ | 1797366776264130560 |
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| author | Ming Li Mengyang Liu Ji Yang Xiuyuan Wang Tianbao Ye Junxia Huang Xinzhi Xu Xuefeng Zhao Hongliang Lu |
| author_facet | Ming Li Mengyang Liu Ji Yang Xiuyuan Wang Tianbao Ye Junxia Huang Xinzhi Xu Xuefeng Zhao Hongliang Lu |
| author_sort | Ming Li |
| collection | DOAJ |
| description | Objective To determine the validity of a hardness sensor to objectively assess skin induration in patients with systemic sclerosis, and to compare the hardness sensor with the modified Rodnan skin score (MRSS) and a durometer.Methods The skin induration was measured in two assessments: a Latin square experiment to examine the hardness sensor’s intraobserver and interobserver reliability; and a longitudinal cohort to evaluate the distribution of hardness sensor measurements, the correlation between hardness sensor, durometer and MRSS, and the sensitivity to change in skin hardness. Other outcome data collected included the health assessment questionnaire (HAQ) disability index and Keitel function test (KTF) score.Results The reliability of the hardness sensor was excellent, with high intraobserver and interobserver intraclass correlation coefficients (0.97; 0.96), which was higher than MRSS (0.86; 0.74). Interobserver reproducibility of hardness sensor was only poor in abdomen (0.38), yet for durometer it was poor in face (0.11) and abdomen (0.33). The hardness sensor score provided a greater dynamic evaluation range than MRSS. Total hardness sensor score correlated well with MRSS (r=0.90, p<0.001), total durometer score (r=0.95, p<0.001), HAQ disability index (r=0.70, p<0.001) and KTF score (r=0.66, p<0.001). Change in hardness sensor score also correlated with change in MRSS (r=0.78, p<0.001), total durometer score (r=0.85, p<0.001), HAQ disability index (r=0.76, p<0.001) and KTF score (r=0.67, p<0.001).Conclusion The hardness sensor showed greater reproducibility and accuracy than MRSS, and more application sites than durometer; it can also reflect patients’ self-assessments and function test outcomes. |
| first_indexed | 2024-03-08T17:08:32Z |
| format | Article |
| id | doaj.art-1426c85bd9f046a7a3e1263a53cfd9f7 |
| institution | Directory Open Access Journal |
| issn | 2056-5933 |
| language | English |
| last_indexed | 2024-03-08T17:08:32Z |
| publishDate | 2023-10-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | RMD Open |
| spelling | doaj.art-1426c85bd9f046a7a3e1263a53cfd9f72024-01-04T01:25:07ZengBMJ Publishing GroupRMD Open2056-59332023-10-019410.1136/rmdopen-2023-003512A stretchable hardness sensor for the assessment of skin disease in systemic sclerosisMing Li0Mengyang Liu1Ji Yang2Xiuyuan Wang3Tianbao Ye4Junxia Huang5Xinzhi Xu6Xuefeng Zhao7Hongliang Lu8Department of Dermatology, Zhongshan Hospital Fudan University, Shanghai, ChinaFudan University, Shanghai, ChinaDepartment of Dermatology, Zhongshan Hospital Fudan University, Shanghai, ChinaDepartment of Dermatology, Zhongshan Hospital Fudan University, Shanghai, ChinaShanghai Sixth People`s Hospital, Shanghai, ChinaDepartment of Dermatology, Zhongshan Hospital Fudan University, Shanghai, ChinaDepartment of Dermatology, Zhongshan Hospital Fudan University, Shanghai, ChinaFudan University, Shanghai, ChinaFudan University, Shanghai, ChinaObjective To determine the validity of a hardness sensor to objectively assess skin induration in patients with systemic sclerosis, and to compare the hardness sensor with the modified Rodnan skin score (MRSS) and a durometer.Methods The skin induration was measured in two assessments: a Latin square experiment to examine the hardness sensor’s intraobserver and interobserver reliability; and a longitudinal cohort to evaluate the distribution of hardness sensor measurements, the correlation between hardness sensor, durometer and MRSS, and the sensitivity to change in skin hardness. Other outcome data collected included the health assessment questionnaire (HAQ) disability index and Keitel function test (KTF) score.Results The reliability of the hardness sensor was excellent, with high intraobserver and interobserver intraclass correlation coefficients (0.97; 0.96), which was higher than MRSS (0.86; 0.74). Interobserver reproducibility of hardness sensor was only poor in abdomen (0.38), yet for durometer it was poor in face (0.11) and abdomen (0.33). The hardness sensor score provided a greater dynamic evaluation range than MRSS. Total hardness sensor score correlated well with MRSS (r=0.90, p<0.001), total durometer score (r=0.95, p<0.001), HAQ disability index (r=0.70, p<0.001) and KTF score (r=0.66, p<0.001). Change in hardness sensor score also correlated with change in MRSS (r=0.78, p<0.001), total durometer score (r=0.85, p<0.001), HAQ disability index (r=0.76, p<0.001) and KTF score (r=0.67, p<0.001).Conclusion The hardness sensor showed greater reproducibility and accuracy than MRSS, and more application sites than durometer; it can also reflect patients’ self-assessments and function test outcomes.https://rmdopen.bmj.com/content/9/4/e003512.full |
| spellingShingle | Ming Li Mengyang Liu Ji Yang Xiuyuan Wang Tianbao Ye Junxia Huang Xinzhi Xu Xuefeng Zhao Hongliang Lu A stretchable hardness sensor for the assessment of skin disease in systemic sclerosis RMD Open |
| title | A stretchable hardness sensor for the assessment of skin disease in systemic sclerosis |
| title_full | A stretchable hardness sensor for the assessment of skin disease in systemic sclerosis |
| title_fullStr | A stretchable hardness sensor for the assessment of skin disease in systemic sclerosis |
| title_full_unstemmed | A stretchable hardness sensor for the assessment of skin disease in systemic sclerosis |
| title_short | A stretchable hardness sensor for the assessment of skin disease in systemic sclerosis |
| title_sort | stretchable hardness sensor for the assessment of skin disease in systemic sclerosis |
| url | https://rmdopen.bmj.com/content/9/4/e003512.full |
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