CRISPR/Cas9 RNP-assisted validation of palmarumycin biosynthetic gene cluster in Lophiotrema sp. F6932

CRISPR/Cas9 RNP-assisted validation of palmarumycin biosynthetic gene cluster in Lophiotrema sp. F6932

Lophiotrema is a genus of ascomycetous fungi within the family Lophiotremataceae. Members of this genus have been isolated as endophytes from a wide range of host plants and also from plant debris within terrestrial and marine habitats, where they are thought to function as saprobes. Lophiotrema sp....

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Bibliographic Details
Main Authors: Martin Muthee Gakuubi, Kuan Chieh Ching, Madhaiyan Munusamy, Mario Wibowo, Chun Teck Lim, Guang-Lei Ma, Zhao-Xun Liang, Yoganathan Kanagasundaram, Siew Bee Ng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Microbiology
Subjects:
CRISPR-Cas9
ketosynthase domain
Lophiotrema sp.
palmarumycin
polyketide synthases
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1012115/full

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