A human skeletal muscle stem/myotube model reveals multiple signaling targets of cancer secretome in skeletal muscle

A human skeletal muscle stem/myotube model reveals multiple signaling targets of cancer secretome in skeletal muscle

Summary: Skeletal muscle dysfunction or reprogramming due to the effects of the cancer secretome is observed in multiple malignancies. Although mouse models are routinely used to study skeletal muscle defects in cancer, because of species specificity of certain cytokines/chemokines in the secretome,...

Full description

Bibliographic Details
Main Authors: Ruizhong Wang, Brijesh Kumar, Poornima Bhat-Nakshatri, Aditi S. Khatpe, Michael P. Murphy, Kristen E. Wanczyk, Edward Simpson, Duojiao Chen, Hongyu Gao, Yunlong Liu, Emma H. Doud, Amber L. Mosley, Harikrishna Nakshatri
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:iScience
Subjects:
Cancer systems biology
Cell biology
Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223006181

Similar Items

Similar Items