Ubiquitin and Not Only Unfolded Domains Drives Toscana Virus Non-Structural NSs Protein Degradation

Ubiquitin and Not Only Unfolded Domains Drives Toscana Virus Non-Structural NSs Protein Degradation

The non-structural protein NSs of the <i>Phenuiviridae</i> family members appears to have a role in the host immunity escape. The stability of Toscana virus (TOSV) NSs protein was tested by a cycloheximide (CHX) chase approach on cells transfected with NSs deleted versions fused to a rep...

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Bibliographic Details
Main Authors: Gianni Gori Savellini, Luca Bini, Assunta Gagliardi, Gabriele Anichini, Claudia Gandolfo, Shibily Prathyumnan, Maria Grazia Cusi
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Viruses
Subjects:
ubiquitin-proteasome system
NSs protein
protein stability
Online Access:https://www.mdpi.com/1999-4915/12/10/1153

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