Exposure to Mycobacterium remodels alveolar macrophages and the early innate response to Mycobacterium tuberculosis infection.

Exposure to Mycobacterium remodels alveolar macrophages and the early innate response to Mycobacterium tuberculosis infection.

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Alveolar macrophages (AMs) play a critical role during Mycobacterium tuberculosis (Mtb) infection as the first cells in the lung to encounter bacteria. We previously showed that AMs initially respond to Mtb in vivo by mounting a cell-protective, rather than pro-inflammatory response. However, the pl...

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Bibliographic Details
Main Authors: Dat Mai, Ana Jahn, Tara Murray, Michael Morikubo, Pamelia N Lim, Maritza M Cervantes, Linh K Pham, Johannes Nemeth, Kevin Urdahl, Alan H Diercks, Alan Aderem, Alissa C Rothchild
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011871&type=printable

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