Role of astroglial Connexin 43 in pneumolysin cytotoxicity and during pneumococcal meningitis.

Role of astroglial Connexin 43 in pneumolysin cytotoxicity and during pneumococcal meningitis.

Streptococcus pneumoniae or pneumococcus (PN) is a major causative agent of bacterial meningitis with high mortality in young infants and elderly people worldwide. The mechanism underlying PN crossing of the blood brain barrier (BBB) and specifically, the role of non-endothelial cells of the neurova...

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Bibliographic Details
Main Authors: Chakir Bello, Yasmine Smail, Vincent Sainte-Rose, Isabelle Podglajen, Alice Gilbert, Vanessa Moreira, Fabrice Chrétien, Martine Cohen Salmon, Guy Tran Van Nhieu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009152

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