Vaccine Effectiveness against DS-1–Like Rotavirus Strains in Infants with Acute Gastroenteritis, Malawi, 2013–2015

Atypical DS-1–like G1P[8] rotaviruses emerged in 2013 in Malawi after rotavirus vaccine introduction. Vaccine effectiveness among infants hospitalized with acute DS-1–like G1P[8] rotavirus gastroenteritis was 85.6% (95% CI 34.4%–96.8%). These findings suggest that vaccine provides protection against...

Full description

Bibliographic Details
Main Authors: Khuzwayo C. Jere, Naor Bar-Zeev, Adams Chande, Aisleen Bennett, Louisa Pollock, Pedro F. Sanchez-Lopez, Osamu Nakagomi, Jacqueline E. Tate, Umesh D. Parashar, Robert S. Heyderman, Neil French, Miren Iturriza-Gomara, Nigel A. Cunliffe
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2019-09-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/25/9/19-0258_article
_version_ 1818197216772227072
author Khuzwayo C. Jere
Naor Bar-Zeev
Adams Chande
Aisleen Bennett
Louisa Pollock
Pedro F. Sanchez-Lopez
Osamu Nakagomi
Jacqueline E. Tate
Umesh D. Parashar
Robert S. Heyderman
Neil French
Miren Iturriza-Gomara
Nigel A. Cunliffe
author_facet Khuzwayo C. Jere
Naor Bar-Zeev
Adams Chande
Aisleen Bennett
Louisa Pollock
Pedro F. Sanchez-Lopez
Osamu Nakagomi
Jacqueline E. Tate
Umesh D. Parashar
Robert S. Heyderman
Neil French
Miren Iturriza-Gomara
Nigel A. Cunliffe
author_sort Khuzwayo C. Jere
collection DOAJ
description Atypical DS-1–like G1P[8] rotaviruses emerged in 2013 in Malawi after rotavirus vaccine introduction. Vaccine effectiveness among infants hospitalized with acute DS-1–like G1P[8] rotavirus gastroenteritis was 85.6% (95% CI 34.4%–96.8%). These findings suggest that vaccine provides protection against these strains despite their emergence coinciding with vaccine introduction.
first_indexed 2024-12-12T01:46:27Z
format Article
id doaj.art-1441846bc0354b37830202bd3c8ec33d
institution Directory Open Access Journal
issn 1080-6040
1080-6059
language English
last_indexed 2024-12-12T01:46:27Z
publishDate 2019-09-01
publisher Centers for Disease Control and Prevention
record_format Article
series Emerging Infectious Diseases
spelling doaj.art-1441846bc0354b37830202bd3c8ec33d2022-12-22T00:42:34ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592019-09-012591734173710.3201/eid2509.190258Vaccine Effectiveness against DS-1–Like Rotavirus Strains in Infants with Acute Gastroenteritis, Malawi, 2013–2015Khuzwayo C. JereNaor Bar-ZeevAdams ChandeAisleen BennettLouisa PollockPedro F. Sanchez-LopezOsamu NakagomiJacqueline E. TateUmesh D. ParasharRobert S. HeydermanNeil FrenchMiren Iturriza-GomaraNigel A. CunliffeAtypical DS-1–like G1P[8] rotaviruses emerged in 2013 in Malawi after rotavirus vaccine introduction. Vaccine effectiveness among infants hospitalized with acute DS-1–like G1P[8] rotavirus gastroenteritis was 85.6% (95% CI 34.4%–96.8%). These findings suggest that vaccine provides protection against these strains despite their emergence coinciding with vaccine introduction.https://wwwnc.cdc.gov/eid/article/25/9/19-0258_articlerotavirusvaccine effectivenessgenome constellationgenotypingwhole-genome sequencingviruses
spellingShingle Khuzwayo C. Jere
Naor Bar-Zeev
Adams Chande
Aisleen Bennett
Louisa Pollock
Pedro F. Sanchez-Lopez
Osamu Nakagomi
Jacqueline E. Tate
Umesh D. Parashar
Robert S. Heyderman
Neil French
Miren Iturriza-Gomara
Nigel A. Cunliffe
Vaccine Effectiveness against DS-1–Like Rotavirus Strains in Infants with Acute Gastroenteritis, Malawi, 2013–2015
Emerging Infectious Diseases
rotavirus
vaccine effectiveness
genome constellation
genotyping
whole-genome sequencing
viruses
title Vaccine Effectiveness against DS-1–Like Rotavirus Strains in Infants with Acute Gastroenteritis, Malawi, 2013–2015
title_full Vaccine Effectiveness against DS-1–Like Rotavirus Strains in Infants with Acute Gastroenteritis, Malawi, 2013–2015
title_fullStr Vaccine Effectiveness against DS-1–Like Rotavirus Strains in Infants with Acute Gastroenteritis, Malawi, 2013–2015
title_full_unstemmed Vaccine Effectiveness against DS-1–Like Rotavirus Strains in Infants with Acute Gastroenteritis, Malawi, 2013–2015
title_short Vaccine Effectiveness against DS-1–Like Rotavirus Strains in Infants with Acute Gastroenteritis, Malawi, 2013–2015
title_sort vaccine effectiveness against ds 1 like rotavirus strains in infants with acute gastroenteritis malawi 2013 2015
topic rotavirus
vaccine effectiveness
genome constellation
genotyping
whole-genome sequencing
viruses
url https://wwwnc.cdc.gov/eid/article/25/9/19-0258_article
work_keys_str_mv AT khuzwayocjere vaccineeffectivenessagainstds1likerotavirusstrainsininfantswithacutegastroenteritismalawi20132015
AT naorbarzeev vaccineeffectivenessagainstds1likerotavirusstrainsininfantswithacutegastroenteritismalawi20132015
AT adamschande vaccineeffectivenessagainstds1likerotavirusstrainsininfantswithacutegastroenteritismalawi20132015
AT aisleenbennett vaccineeffectivenessagainstds1likerotavirusstrainsininfantswithacutegastroenteritismalawi20132015
AT louisapollock vaccineeffectivenessagainstds1likerotavirusstrainsininfantswithacutegastroenteritismalawi20132015
AT pedrofsanchezlopez vaccineeffectivenessagainstds1likerotavirusstrainsininfantswithacutegastroenteritismalawi20132015
AT osamunakagomi vaccineeffectivenessagainstds1likerotavirusstrainsininfantswithacutegastroenteritismalawi20132015
AT jacquelineetate vaccineeffectivenessagainstds1likerotavirusstrainsininfantswithacutegastroenteritismalawi20132015
AT umeshdparashar vaccineeffectivenessagainstds1likerotavirusstrainsininfantswithacutegastroenteritismalawi20132015
AT robertsheyderman vaccineeffectivenessagainstds1likerotavirusstrainsininfantswithacutegastroenteritismalawi20132015
AT neilfrench vaccineeffectivenessagainstds1likerotavirusstrainsininfantswithacutegastroenteritismalawi20132015
AT mireniturrizagomara vaccineeffectivenessagainstds1likerotavirusstrainsininfantswithacutegastroenteritismalawi20132015
AT nigelacunliffe vaccineeffectivenessagainstds1likerotavirusstrainsininfantswithacutegastroenteritismalawi20132015