The increasing burden of pancreatic cancer in Brazil from 2000 to 2019: estimates from the Global Burden of Disease Study 2019.
Abstract INTRODUCTION: Pancreatic cancer is increasing worldwide. The burden of pancreatic cancer in Brazil and its states was analyzed and compared with that from the USA and China. METHODS: This is a descriptive study of the incidence and mortality estimates from the Global Burden of Disease 20...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira de Medicina Tropical (SBMT)
2022-01-01
|
| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822022000500308&tlng=en |
| _version_ | 1818264048172531712 |
|---|---|
| author | Diogo Oliveira Chaves Aline Cândida Bastos Alessandra Maciel Almeida Maximiliano Ribeiro Guerra Maria Teresa Bustamante Teixeira Ana Paula Souto Melo Valéria Maria de Azeredo Passos |
| author_facet | Diogo Oliveira Chaves Aline Cândida Bastos Alessandra Maciel Almeida Maximiliano Ribeiro Guerra Maria Teresa Bustamante Teixeira Ana Paula Souto Melo Valéria Maria de Azeredo Passos |
| author_sort | Diogo Oliveira Chaves |
| collection | DOAJ |
| description | Abstract INTRODUCTION: Pancreatic cancer is increasing worldwide. The burden of pancreatic cancer in Brazil and its states was analyzed and compared with that from the USA and China. METHODS: This is a descriptive study of the incidence and mortality estimates from the Global Burden of Disease 2019 study, from 2000 to 2019. The Brazilian states presenting the highest and lowest socio-demographic index (SDI) were selected from each of the five regions. The SDI consists of the per capita income, education, and fertility rate of each population. RESULTS: A significant increase was found in age-standardized incidence and mortality of pancreatic cancer in all three countries, with differences in magnitude and annual increases. In Brazil, this incidence rose from 5.33 [95% Uncertainty Interval (UI): 5.06- 5.51] to 6.16 (95% UI: 5.68- 6.53) per 100,000 inhabitants. China and the Brazilian states with the lowest SDI, such as Pará and Maranhão, showed lower incidence and mortality rates, although presenting the highest annual increases. No difference was found between the sexes. A higher mortality rate was observed for those individuals of 70+ years, which was three to four times higher than those aged 50 to 69 years. CONCLUSIONS: The increasing burden of pancreatic cancer in the studied countries, and the higher estimates for the elderly in a fast-aging country such as Brazil, indicates that more resources and health policies will be necessary. The greatest increase in the states with lower SDI reflects inequalities in the access to diagnosis and registries of this cancer. |
| first_indexed | 2024-12-12T19:28:43Z |
| format | Article |
| id | doaj.art-1444629366cf4853befc9dd3a484482a |
| institution | Directory Open Access Journal |
| issn | 1678-9849 |
| language | English |
| last_indexed | 2024-12-12T19:28:43Z |
| publishDate | 2022-01-01 |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-1444629366cf4853befc9dd3a484482a2022-12-22T00:14:28ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492022-01-0155suppl 110.1590/0037-8682-0271-2021The increasing burden of pancreatic cancer in Brazil from 2000 to 2019: estimates from the Global Burden of Disease Study 2019.Diogo Oliveira Chaveshttps://orcid.org/0000-0002-0451-2957Aline Cândida Bastoshttps://orcid.org/0000-0001-8641-2767Alessandra Maciel Almeidahttps://orcid.org/0000-0003-0138-9401Maximiliano Ribeiro Guerrahttps://orcid.org/0000-0003-0234-7190Maria Teresa Bustamante Teixeirahttps://orcid.org/0000-0003-0727-4170Ana Paula Souto Melohttps://orcid.org/0000-0002-9955-0824Valéria Maria de Azeredo Passoshttps://orcid.org/0000-0003-2829-5798Abstract INTRODUCTION: Pancreatic cancer is increasing worldwide. The burden of pancreatic cancer in Brazil and its states was analyzed and compared with that from the USA and China. METHODS: This is a descriptive study of the incidence and mortality estimates from the Global Burden of Disease 2019 study, from 2000 to 2019. The Brazilian states presenting the highest and lowest socio-demographic index (SDI) were selected from each of the five regions. The SDI consists of the per capita income, education, and fertility rate of each population. RESULTS: A significant increase was found in age-standardized incidence and mortality of pancreatic cancer in all three countries, with differences in magnitude and annual increases. In Brazil, this incidence rose from 5.33 [95% Uncertainty Interval (UI): 5.06- 5.51] to 6.16 (95% UI: 5.68- 6.53) per 100,000 inhabitants. China and the Brazilian states with the lowest SDI, such as Pará and Maranhão, showed lower incidence and mortality rates, although presenting the highest annual increases. No difference was found between the sexes. A higher mortality rate was observed for those individuals of 70+ years, which was three to four times higher than those aged 50 to 69 years. CONCLUSIONS: The increasing burden of pancreatic cancer in the studied countries, and the higher estimates for the elderly in a fast-aging country such as Brazil, indicates that more resources and health policies will be necessary. The greatest increase in the states with lower SDI reflects inequalities in the access to diagnosis and registries of this cancer.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822022000500308&tlng=enPancreatic câncerMortalityIncidenceSocial inequality |
| spellingShingle | Diogo Oliveira Chaves Aline Cândida Bastos Alessandra Maciel Almeida Maximiliano Ribeiro Guerra Maria Teresa Bustamante Teixeira Ana Paula Souto Melo Valéria Maria de Azeredo Passos The increasing burden of pancreatic cancer in Brazil from 2000 to 2019: estimates from the Global Burden of Disease Study 2019. Revista da Sociedade Brasileira de Medicina Tropical Pancreatic câncer Mortality Incidence Social inequality |
| title | The increasing burden of pancreatic cancer in Brazil from 2000 to 2019: estimates from the Global Burden of Disease Study 2019. |
| title_full | The increasing burden of pancreatic cancer in Brazil from 2000 to 2019: estimates from the Global Burden of Disease Study 2019. |
| title_fullStr | The increasing burden of pancreatic cancer in Brazil from 2000 to 2019: estimates from the Global Burden of Disease Study 2019. |
| title_full_unstemmed | The increasing burden of pancreatic cancer in Brazil from 2000 to 2019: estimates from the Global Burden of Disease Study 2019. |
| title_short | The increasing burden of pancreatic cancer in Brazil from 2000 to 2019: estimates from the Global Burden of Disease Study 2019. |
| title_sort | increasing burden of pancreatic cancer in brazil from 2000 to 2019 estimates from the global burden of disease study 2019 |
| topic | Pancreatic câncer Mortality Incidence Social inequality |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822022000500308&tlng=en |
| work_keys_str_mv | AT diogooliveirachaves theincreasingburdenofpancreaticcancerinbrazilfrom2000to2019estimatesfromtheglobalburdenofdiseasestudy2019 AT alinecandidabastos theincreasingburdenofpancreaticcancerinbrazilfrom2000to2019estimatesfromtheglobalburdenofdiseasestudy2019 AT alessandramacielalmeida theincreasingburdenofpancreaticcancerinbrazilfrom2000to2019estimatesfromtheglobalburdenofdiseasestudy2019 AT maximilianoribeiroguerra theincreasingburdenofpancreaticcancerinbrazilfrom2000to2019estimatesfromtheglobalburdenofdiseasestudy2019 AT mariateresabustamanteteixeira theincreasingburdenofpancreaticcancerinbrazilfrom2000to2019estimatesfromtheglobalburdenofdiseasestudy2019 AT anapaulasoutomelo theincreasingburdenofpancreaticcancerinbrazilfrom2000to2019estimatesfromtheglobalburdenofdiseasestudy2019 AT valeriamariadeazeredopassos theincreasingburdenofpancreaticcancerinbrazilfrom2000to2019estimatesfromtheglobalburdenofdiseasestudy2019 AT diogooliveirachaves increasingburdenofpancreaticcancerinbrazilfrom2000to2019estimatesfromtheglobalburdenofdiseasestudy2019 AT alinecandidabastos increasingburdenofpancreaticcancerinbrazilfrom2000to2019estimatesfromtheglobalburdenofdiseasestudy2019 AT alessandramacielalmeida increasingburdenofpancreaticcancerinbrazilfrom2000to2019estimatesfromtheglobalburdenofdiseasestudy2019 AT maximilianoribeiroguerra increasingburdenofpancreaticcancerinbrazilfrom2000to2019estimatesfromtheglobalburdenofdiseasestudy2019 AT mariateresabustamanteteixeira increasingburdenofpancreaticcancerinbrazilfrom2000to2019estimatesfromtheglobalburdenofdiseasestudy2019 AT anapaulasoutomelo increasingburdenofpancreaticcancerinbrazilfrom2000to2019estimatesfromtheglobalburdenofdiseasestudy2019 AT valeriamariadeazeredopassos increasingburdenofpancreaticcancerinbrazilfrom2000to2019estimatesfromtheglobalburdenofdiseasestudy2019 |