Fetal Cerebellar Vermis Circumference Measured by 2-Dimensional Ultrasound Scan: Reference Range, Feasibility and Reproducibility
Purpose: To provide 2-dimensional ultrasonographic (2D-US) normograms of cerebellar vermis biometry, as well as to evaluate the feasibility and the reproducibility of these measurements in clinical practice. Materials and Methods: A prospective cross-sectional study of 328 normal singleton pregnanc...
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| Format: | Article |
| Language: | English |
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Georg Thieme Verlag KG
2016-11-01
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| Series: | Ultrasound International Open |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-119952 |
| _version_ | 1818368242625806336 |
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| author | M. Spinelli C. Sica L. D. Meglio D. Bolla L. Raio D. Surbek |
| author_facet | M. Spinelli C. Sica L. D. Meglio D. Bolla L. Raio D. Surbek |
| author_sort | M. Spinelli |
| collection | DOAJ |
| description | Purpose: To provide 2-dimensional ultrasonographic (2D-US) normograms of cerebellar vermis biometry, as well as to evaluate the feasibility and the reproducibility of these measurements in clinical practice.
Materials and Methods: A prospective cross-sectional study of 328 normal singleton pregnancies between 18 and 33 weeks of gestation. Measurements of the fetal cerebellar vermis circumference (VC) in the mid-sagittal plane were performed by both a senior and a junior operator using 2D-US. VC as a function of gestational age (GA) was expressed by regression equations. In 24 fetuses 3-dimensional (3D) reconstructed planes were obtained in order to allow comparisons with 2D-US measurements. The agreement between 2D and 3D measurements and the interobserver variability were assessed by interclass correlation coefficients (ICC).
Results: Satisfactory vermis measurements could be obtained in 89.9% of cases. The VC (constant= − 12.21; slope=2.447; r=0.887, p<0.0001) correlated linearly with GA. A high degree of consistency was observed between 2D and 3D ultrasound measurements (ICC=0.846 95% CI 679–0.930) as well as between measurements obtained by different examiners (ICC=0.890 95% CI 989–0.945).
Conclusion: 2-dimensional ultrasonographic measurements of cerebellar vermis throughout gestation in the mid-sagittal view seem to be feasible and reproducible enough to be potentially used in clinical practice. Such measurements may supply a tool for accurate identification of posterior fossa anomalies, providing the basis for proper counseling and management and of these conditions. |
| first_indexed | 2024-12-13T23:04:50Z |
| format | Article |
| id | doaj.art-144566d93a6f4754a12b15b6c5002ac7 |
| institution | Directory Open Access Journal |
| issn | 2509-596X 2199-7152 |
| language | English |
| last_indexed | 2024-12-13T23:04:50Z |
| publishDate | 2016-11-01 |
| publisher | Georg Thieme Verlag KG |
| record_format | Article |
| series | Ultrasound International Open |
| spelling | doaj.art-144566d93a6f4754a12b15b6c5002ac72022-12-21T23:28:19ZengGeorg Thieme Verlag KGUltrasound International Open2509-596X2199-71522016-11-010204E124E12810.1055/s-0042-119952Fetal Cerebellar Vermis Circumference Measured by 2-Dimensional Ultrasound Scan: Reference Range, Feasibility and ReproducibilityM. Spinelli0C. Sica1L. D. Meglio2D. Bolla3L. Raio4D. Surbek5Department of Clinical Research, Prenatal Medicine, Inselspital Bern Universitatsklinik fur Frauenheilkunde, Bern, SwitzerlandObstetrics and Gynecology, Private Centre "Diagnostica ecografica e prenatale Aniello Di Meglio s.r.l.", Naples, ItalyObstetrics and Gynecology, Private Centre "Diagnostica ecografica e prenatale Aniello Di Meglio s.r.l.", Naples, ItalyOB/GYN, University of Bern, Bern, SwitzerlandOB/GYN, University of Bern, Bern, SwitzerlandOB & GYN, Inselspital, Bern, SwitzerlandPurpose: To provide 2-dimensional ultrasonographic (2D-US) normograms of cerebellar vermis biometry, as well as to evaluate the feasibility and the reproducibility of these measurements in clinical practice. Materials and Methods: A prospective cross-sectional study of 328 normal singleton pregnancies between 18 and 33 weeks of gestation. Measurements of the fetal cerebellar vermis circumference (VC) in the mid-sagittal plane were performed by both a senior and a junior operator using 2D-US. VC as a function of gestational age (GA) was expressed by regression equations. In 24 fetuses 3-dimensional (3D) reconstructed planes were obtained in order to allow comparisons with 2D-US measurements. The agreement between 2D and 3D measurements and the interobserver variability were assessed by interclass correlation coefficients (ICC). Results: Satisfactory vermis measurements could be obtained in 89.9% of cases. The VC (constant= − 12.21; slope=2.447; r=0.887, p<0.0001) correlated linearly with GA. A high degree of consistency was observed between 2D and 3D ultrasound measurements (ICC=0.846 95% CI 679–0.930) as well as between measurements obtained by different examiners (ICC=0.890 95% CI 989–0.945). Conclusion: 2-dimensional ultrasonographic measurements of cerebellar vermis throughout gestation in the mid-sagittal view seem to be feasible and reproducible enough to be potentially used in clinical practice. Such measurements may supply a tool for accurate identification of posterior fossa anomalies, providing the basis for proper counseling and management and of these conditions.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-119952prenatal diagnosisultrasound 2dcerebellar vermis |
| spellingShingle | M. Spinelli C. Sica L. D. Meglio D. Bolla L. Raio D. Surbek Fetal Cerebellar Vermis Circumference Measured by 2-Dimensional Ultrasound Scan: Reference Range, Feasibility and Reproducibility Ultrasound International Open prenatal diagnosis ultrasound 2d cerebellar vermis |
| title | Fetal Cerebellar Vermis Circumference Measured by 2-Dimensional Ultrasound Scan: Reference Range, Feasibility and Reproducibility |
| title_full | Fetal Cerebellar Vermis Circumference Measured by 2-Dimensional Ultrasound Scan: Reference Range, Feasibility and Reproducibility |
| title_fullStr | Fetal Cerebellar Vermis Circumference Measured by 2-Dimensional Ultrasound Scan: Reference Range, Feasibility and Reproducibility |
| title_full_unstemmed | Fetal Cerebellar Vermis Circumference Measured by 2-Dimensional Ultrasound Scan: Reference Range, Feasibility and Reproducibility |
| title_short | Fetal Cerebellar Vermis Circumference Measured by 2-Dimensional Ultrasound Scan: Reference Range, Feasibility and Reproducibility |
| title_sort | fetal cerebellar vermis circumference measured by 2 dimensional ultrasound scan reference range feasibility and reproducibility |
| topic | prenatal diagnosis ultrasound 2d cerebellar vermis |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-119952 |
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