Cardiac, renal and vascular complications in the diabetic patient

Type 2 diabetes has long been known to be associated with an increased risk of cardiovascular disease. Patients with type 2 diabetes have also been shown to benefit more from antihypertensive therapy than do non-diabetics with hypertension. The benefits of aggressive antihypertensive therapy are ref...

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Bibliographic Details
Main Author: Alberto Zanchetti
Format: Article
Language:English
Published: SAGE Publications 2000-06-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:http://jra.sagepub.com/content/1/2_suppl/S21.full.pdf
Description
Summary:Type 2 diabetes has long been known to be associated with an increased risk of cardiovascular disease. Patients with type 2 diabetes have also been shown to benefit more from antihypertensive therapy than do non-diabetics with hypertension. The benefits of aggressive antihypertensive therapy are reflected in the recent reduction of blood pressure (BP) targets in international guidelines. Drugs acting on the reninangiotensin-aldosterone system (RAAS) have well-documented efficacy, and results from large-scale trials with highly selective angiotensin II (Ang II) receptor blockers (ARBs), such as valsartan, are awaited. The VALUE trial will provide the largest body of information yet on the comparative benefits of using an ARB or calcium channel blocker in hypertensive patients with diabetes.
ISSN:1470-3203
1752-8976