Practical handling of AIO admixtures – Guidelines on Parenteral Nutrition, Chapter 10
All-in-one admixtures (AIO-admixtures) provide safe, effective and low-risk PN (parenteral nutrition) for practically all indications and applications. Water, energy (carbohydrates and lipids), amino acids, vitamins and trace elements are infused together with PN either as industrially-manufactured...
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| Format: | Article |
| Language: | deu |
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German Medical Science GMS Publishing House
2009-11-01
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| Series: | GMS German Medical Science |
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| Online Access: | http://www.egms.de/static/en/journals/gms/2009-7/000077.shtml |
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| author | Stanga, Z. Franken, C. Mühlebach, S. Working group for developing the guidelines for parenteral nutrition of The German Association for Nutritional Medicine |
| author_facet | Stanga, Z. Franken, C. Mühlebach, S. Working group for developing the guidelines for parenteral nutrition of The German Association for Nutritional Medicine |
| author_sort | Stanga, Z. |
| collection | DOAJ |
| description | All-in-one admixtures (AIO-admixtures) provide safe, effective and low-risk PN (parenteral nutrition) for practically all indications and applications. Water, energy (carbohydrates and lipids), amino acids, vitamins and trace elements are infused together with PN either as industrially-manufactured AIO admixtures provided as two- or three-chamber bags (shelf life usually more than 12 months) completed with electrolytes and micronutrients where appropriate or as individually compounded ready-to-use AIO admixtures (compounding, usually prepared by a pharmacy on either a daily or weekly basis and stored at 2–8°C). Physico-chemical and microbial stability of an AIO admixture is essential for the safety and effectiveness of patient-specific PN, and its assurance requires specialist pharmaceutical knowledge. The stability should be documented for an application period of 24 (–48) hours. It is advisable to offer a limited selection of different PN regimes in each hospital. For reasons of drug and medication safety, PN admixtures prepared for individual patients must be correctly labelled and specifications for storage conditions must also be followed during transport. Monitoring is required where applicable. Micronutrients are usually administered separately to AIO admixtures. In case compatibility and stability have been well documented trace elements and/or combination preparations including water-soluble or water-soluble/fat soluble vitamin supplements can be added to PN admixtures under strict aseptic conditions. AIO admixtures are usually not used as vehicles for drugs (incompatibilities). |
| first_indexed | 2024-12-12T21:49:41Z |
| format | Article |
| id | doaj.art-144ecc5ca76047599dfd04b9a177c54a |
| institution | Directory Open Access Journal |
| issn | 1612-3174 |
| language | deu |
| last_indexed | 2024-12-12T21:49:41Z |
| publishDate | 2009-11-01 |
| publisher | German Medical Science GMS Publishing House |
| record_format | Article |
| series | GMS German Medical Science |
| spelling | doaj.art-144ecc5ca76047599dfd04b9a177c54a2022-12-22T00:10:50ZdeuGerman Medical Science GMS Publishing HouseGMS German Medical Science1612-31742009-11-017Doc18Practical handling of AIO admixtures – Guidelines on Parenteral Nutrition, Chapter 10Stanga, Z.Franken, C.Mühlebach, S.Working group for developing the guidelines for parenteral nutrition of The German Association for Nutritional MedicineAll-in-one admixtures (AIO-admixtures) provide safe, effective and low-risk PN (parenteral nutrition) for practically all indications and applications. Water, energy (carbohydrates and lipids), amino acids, vitamins and trace elements are infused together with PN either as industrially-manufactured AIO admixtures provided as two- or three-chamber bags (shelf life usually more than 12 months) completed with electrolytes and micronutrients where appropriate or as individually compounded ready-to-use AIO admixtures (compounding, usually prepared by a pharmacy on either a daily or weekly basis and stored at 2–8°C). Physico-chemical and microbial stability of an AIO admixture is essential for the safety and effectiveness of patient-specific PN, and its assurance requires specialist pharmaceutical knowledge. The stability should be documented for an application period of 24 (–48) hours. It is advisable to offer a limited selection of different PN regimes in each hospital. For reasons of drug and medication safety, PN admixtures prepared for individual patients must be correctly labelled and specifications for storage conditions must also be followed during transport. Monitoring is required where applicable. Micronutrients are usually administered separately to AIO admixtures. In case compatibility and stability have been well documented trace elements and/or combination preparations including water-soluble or water-soluble/fat soluble vitamin supplements can be added to PN admixtures under strict aseptic conditions. AIO admixtures are usually not used as vehicles for drugs (incompatibilities).http://www.egms.de/static/en/journals/gms/2009-7/000077.shtmlinfusion systemscompoundingindustrial parenteral nutrition systemsstabilityquality assurance |
| spellingShingle | Stanga, Z. Franken, C. Mühlebach, S. Working group for developing the guidelines for parenteral nutrition of The German Association for Nutritional Medicine Practical handling of AIO admixtures – Guidelines on Parenteral Nutrition, Chapter 10 GMS German Medical Science infusion systems compounding industrial parenteral nutrition systems stability quality assurance |
| title | Practical handling of AIO admixtures – Guidelines on Parenteral Nutrition, Chapter 10 |
| title_full | Practical handling of AIO admixtures – Guidelines on Parenteral Nutrition, Chapter 10 |
| title_fullStr | Practical handling of AIO admixtures – Guidelines on Parenteral Nutrition, Chapter 10 |
| title_full_unstemmed | Practical handling of AIO admixtures – Guidelines on Parenteral Nutrition, Chapter 10 |
| title_short | Practical handling of AIO admixtures – Guidelines on Parenteral Nutrition, Chapter 10 |
| title_sort | practical handling of aio admixtures guidelines on parenteral nutrition chapter 10 |
| topic | infusion systems compounding industrial parenteral nutrition systems stability quality assurance |
| url | http://www.egms.de/static/en/journals/gms/2009-7/000077.shtml |
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