IL-18 and IL-18 binding protein are related to disease severity and parasitemia during falciparum malaria

IL-18 and IL-18 binding protein are related to disease severity and parasitemia during falciparum malaria

Abstract Background Several inflammatory molecules participate in the immune response to malaria. Interleukin (IL)-18 is an inflammatory cytokine activated by NLRP3 inflammasomes. In clinical falciparum malaria, with and without HIV co-infection, data on IL-18 and in particular on its binding protei...

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Bibliographic Details
Main Authors: Kari Otterdal, Aase Berg, Annika E. Michelsen, Arne Yndestad, Sam Patel, Ida Gregersen, Bente Halvorsen, Thor Ueland, Nina Langeland, Pål Aukrust
Format: Article
Language:English
Published: BMC 2021-10-01
Series:BMC Infectious Diseases
Subjects:
IL-18
IL-18bp
Falciparum malaria
HIV
Endothelial cells
Online Access:https://doi.org/10.1186/s12879-021-06751-y

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