Hyodeoxycholic acid protects the neurovascular unit against oxygen-glucose deprivation and reoxygenation-induced injury in vitro

Hyodeoxycholic acid protects the neurovascular unit against oxygen-glucose deprivation and reoxygenation-induced injury in vitro

Calculus bovis is commonly used for the treatment of stroke in traditional Chinese medicine. Hyodeoxycholic acid (HDCA) is a bioactive compound extracted from calculus bovis. When combined with cholic acid, baicalin and jas-minoidin, HDCA prevents hypoxia-reoxygenation-induced brain injury by suppre...

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Bibliographic Details
Main Authors: Chang-Xiang Li, Xue-Qian Wang, Fa-Feng Cheng, Xin Yan, Juan Luo, Qing-Guo Wang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Neural Regeneration Research
Subjects:
hyodeoxycholic acid; oxygen glucose deprivation and reoxygenation; blood-brain barrier permeability; anti-oxidative; anti-inflammatory; anti-apoptotic; brain-derived neurotrophic factor; glial cell line-derived neurotrophic factor; ischemic stroke; in vitro neurovascular unit
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=11;spage=1941;epage=1949;aulast=Li

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