The Functionality of Minimal PiggyBac Transposons in Mammalian Cells

The Functionality of Minimal PiggyBac Transposons in Mammalian Cells

Minimal piggyBac vectors are a modified single-plasmid version of the classical piggyBac delivery system that can be used for stable transgene integration. These vectors have a truncated terminal domain in the delivery cassette and thus, integrate significantly less flanking transposon DNA into host...

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Bibliographic Details
Main Authors: Boris Troyanovsky, Vira Bitko, Viktor Pastukh, Brian Fouty, Victor Solodushko
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
minimal piggyBac vectors
stable gene delivery
transposon
Online Access:http://www.sciencedirect.com/science/article/pii/S216225311730094X

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