At-home bleaching versus whitening toothpastes for treatment of tooth discoloration: a cost-effectiveness analysis
Abstract Objectives This study aimed to analyze the cost-effectiveness of whitening toothpastes and at-home bleaching for the treatment of tooth discoloration. Methodology A cost-effectiveness economic analysis was conducted, and eight randomized clinical trials were selected based on the whiten...
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| Format: | Article |
| Language: | English |
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University of São Paulo
2024-02-01
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| Series: | Journal of Applied Oral Science |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572024000100405&lng=en&tlng=en |
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| author | Mariana Evangelista SANTOS Rênnis Oliveira da SILVA Yuri Wanderley CAVALCANTI Sônia Saeger MEIRELES |
| author_facet | Mariana Evangelista SANTOS Rênnis Oliveira da SILVA Yuri Wanderley CAVALCANTI Sônia Saeger MEIRELES |
| author_sort | Mariana Evangelista SANTOS |
| collection | DOAJ |
| description | Abstract Objectives This study aimed to analyze the cost-effectiveness of whitening toothpastes and at-home bleaching for the treatment of tooth discoloration. Methodology A cost-effectiveness economic analysis was conducted, and eight randomized clinical trials were selected based on the whitening agent product used: blue covarine dentifrices (BCD), hydrogen peroxide dentifrices (HPD), dentifrices without bleaching agents (CD, negative control), and 10% carbamide peroxide (CP10, positive control) for at-home bleaching. The consumer/patient perspective was adopted, macro-costing techniques were used and a decision tree model was performed considering the costs in the American and Brazilian markets. The color change evaluation (ΔE*ab) was used to calculate the effectiveness of tooth bleaching. A probabilistic analysis was performed using a Monte Carlo simulation and incremental cost-effectiveness ratios were obtained. Results CP10 resulted in the highest cost-effectiveness compared to the use of dentifrices in both markets. In Brazil, HPD was more cost-effective than BCD and CD. In the US, the increased costs of HPD and BCD did not generate any whitening benefit compared to CD. Conclusions CP10 was more cost-effective than BCD and HPD for tooth bleaching from the perspectives of the Brazilian and American markets. Decision-making should consider the use of CP10 for treating tooth discoloration. |
| first_indexed | 2024-03-08T05:29:37Z |
| format | Article |
| id | doaj.art-1455de77dc114e88991cb9c46fd6790e |
| institution | Directory Open Access Journal |
| issn | 1678-7765 |
| language | English |
| last_indexed | 2024-03-08T05:29:37Z |
| publishDate | 2024-02-01 |
| publisher | University of São Paulo |
| record_format | Article |
| series | Journal of Applied Oral Science |
| spelling | doaj.art-1455de77dc114e88991cb9c46fd6790e2024-02-06T07:43:16ZengUniversity of São PauloJournal of Applied Oral Science1678-77652024-02-013210.1590/1678-7757-2023-0336At-home bleaching versus whitening toothpastes for treatment of tooth discoloration: a cost-effectiveness analysisMariana Evangelista SANTOShttps://orcid.org/0000-0002-4282-760XRênnis Oliveira da SILVAhttps://orcid.org/0000-0001-8413-8071Yuri Wanderley CAVALCANTIhttps://orcid.org/0000-0002-3570-9904Sônia Saeger MEIRELEShttps://orcid.org/0000-0001-7328-2991Abstract Objectives This study aimed to analyze the cost-effectiveness of whitening toothpastes and at-home bleaching for the treatment of tooth discoloration. Methodology A cost-effectiveness economic analysis was conducted, and eight randomized clinical trials were selected based on the whitening agent product used: blue covarine dentifrices (BCD), hydrogen peroxide dentifrices (HPD), dentifrices without bleaching agents (CD, negative control), and 10% carbamide peroxide (CP10, positive control) for at-home bleaching. The consumer/patient perspective was adopted, macro-costing techniques were used and a decision tree model was performed considering the costs in the American and Brazilian markets. The color change evaluation (ΔE*ab) was used to calculate the effectiveness of tooth bleaching. A probabilistic analysis was performed using a Monte Carlo simulation and incremental cost-effectiveness ratios were obtained. Results CP10 resulted in the highest cost-effectiveness compared to the use of dentifrices in both markets. In Brazil, HPD was more cost-effective than BCD and CD. In the US, the increased costs of HPD and BCD did not generate any whitening benefit compared to CD. Conclusions CP10 was more cost-effective than BCD and HPD for tooth bleaching from the perspectives of the Brazilian and American markets. Decision-making should consider the use of CP10 for treating tooth discoloration.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572024000100405&lng=en&tlng=enCost-benefit analysisDentifricesToothpastesCarbamide peroxideTooth bleaching |
| spellingShingle | Mariana Evangelista SANTOS Rênnis Oliveira da SILVA Yuri Wanderley CAVALCANTI Sônia Saeger MEIRELES At-home bleaching versus whitening toothpastes for treatment of tooth discoloration: a cost-effectiveness analysis Journal of Applied Oral Science Cost-benefit analysis Dentifrices Toothpastes Carbamide peroxide Tooth bleaching |
| title | At-home bleaching versus whitening toothpastes for treatment of tooth discoloration: a cost-effectiveness analysis |
| title_full | At-home bleaching versus whitening toothpastes for treatment of tooth discoloration: a cost-effectiveness analysis |
| title_fullStr | At-home bleaching versus whitening toothpastes for treatment of tooth discoloration: a cost-effectiveness analysis |
| title_full_unstemmed | At-home bleaching versus whitening toothpastes for treatment of tooth discoloration: a cost-effectiveness analysis |
| title_short | At-home bleaching versus whitening toothpastes for treatment of tooth discoloration: a cost-effectiveness analysis |
| title_sort | at home bleaching versus whitening toothpastes for treatment of tooth discoloration a cost effectiveness analysis |
| topic | Cost-benefit analysis Dentifrices Toothpastes Carbamide peroxide Tooth bleaching |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572024000100405&lng=en&tlng=en |
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