Neutrophil metalloproteinase driven spleen damage hampers infection control of trypanosomiasis

Abstract Recent blood transcriptomic analysis of rhodesiense sleeping sickness patients has revealed that neutrophil signature genes and activation markers constitute the top indicators of trypanosomiasis-associated inflammation. Here, we show that Trypanosoma brucei infection results in expansion a...

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Bibliographic Details
Main Authors: Hien Thi Thu Pham, Stefan Magez, Boyoon Choi, Bolortsetseg Baatar, Joohee Jung, Magdalena Radwanska
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41089-w