The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation
Summary: Human primordial germ cells (hPGCs) are the first embryonic progenitors in the germ cell lineage, yet the molecular mechanisms required for hPGC formation are not well characterized. To identify regulatory regions in hPGC development, we used the assay for transposase-accessible chromatin u...
Main Authors: | Di Chen, Wanlu Liu, Jill Zimmerman, William A. Pastor, Rachel Kim, Linzi Hosohama, Jamie Ho, Marianna Aslanyan, Joanna J. Gell, Steven E. Jacobsen, Amander T. Clark |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-12-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124718319223 |
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