A novel peptide defined through phage display for therapeutic protein and vector neuronal targeting
A novel peptide with the binding characteristics of tetanus toxin was identified with phage display, for application in therapeutic protein and vector motor and sensory neuron targeting. A 12mer phage library was biopanned on trisialoganglioside (GT1b) and eluted with the tetanus toxin C fragment (r...
Main Authors: | James K. Liu, Qingshan Teng, Mary Garrity-Moses, Thais Federici, Diana Tanase, Michael J. Imperiale, Nicholas M. Boulis |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2005-08-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S096999610500032X |
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