Macrophage elastase (MMP-12): a pro-inflammatory mediator?

Macrophage elastase (MMP-12): a pro-inflammatory mediator?

As many metalloproteinases (MMPs), macrophage elastase (MMP-12) is able to degrade extracellular matrix components such as elastin and is involved in tissue remodeling processes. Studies using animal models of acute and chronic pulmonary inflammatory diseases, such as pulmonary fibrosis and chronic...

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Bibliographic Details
Main Authors:	Soazig Nénan, Elisabeth Boichot, Vincent Lagente, Claude P Bertrand
Format:	Article
Language:	English
Published:	Fundação Oswaldo Cruz (FIOCRUZ) 2005-03-01
Series:	Memorias do Instituto Oswaldo Cruz
Subjects:	matrix metalloproteianse metalloelastase airway inflammation chronic obstructive pulmonary disease
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000900028

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