GANs-Based Intracoronary Optical Coherence Tomography Image Augmentation for Improved Plaques Characterization Using Deep Neural Networks

Data augmentation using generative adversarial networks (GANs) is vital in the creation of new instances that include imaging modality tasks for improved deep learning classification. In this study, conditional generative adversarial networks (cGANs) were used on a dataset of OCT (Optical Coherence...

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Main Authors: Haroon Zafar, Junaid Zafar, Faisal Sharif
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Optics
Subjects:
Online Access:https://www.mdpi.com/2673-3269/4/2/20
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author Haroon Zafar
Junaid Zafar
Faisal Sharif
author_facet Haroon Zafar
Junaid Zafar
Faisal Sharif
author_sort Haroon Zafar
collection DOAJ
description Data augmentation using generative adversarial networks (GANs) is vital in the creation of new instances that include imaging modality tasks for improved deep learning classification. In this study, conditional generative adversarial networks (cGANs) were used on a dataset of OCT (Optical Coherence Tomography)-acquired images of coronary atrial plaques for synthetic data creation for the first time, and further validated using deep learning architecture. A new OCT images dataset of 51 patients marked by three professionals was created and programmed. We used cGANs to synthetically populate the coronary aerial plaques dataset by factors of 5×, 10×, 50× and 100× from a limited original dataset to enhance its volume and diversification. The loss functions for the generator and the discriminator were set up to generate perfect aliases. The augmented OCT dataset was then used in the training phase of the leading AlexNet architecture. We used cGANs to create synthetic images and envisaged the impact of the ratio of real data to synthetic data on classification accuracy. We illustrated through experiments that augmenting real images with synthetic images by a factor of 50× during training helped improve the test accuracy of the classification architecture for label prediction by 15.8%. Further, we performed training time assessments against a number of iterations to identify optimum time efficiency. Automated plaques detection was found to be in conformity with clinical results using our proposed class conditioning GAN architecture.
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spelling doaj.art-145e749c98b848f28e53dc54c769419f2023-11-18T11:58:23ZengMDPI AGOptics2673-32692023-03-014228829910.3390/opt4020020GANs-Based Intracoronary Optical Coherence Tomography Image Augmentation for Improved Plaques Characterization Using Deep Neural NetworksHaroon Zafar0Junaid Zafar1Faisal Sharif2Lambe Institute for Translational Research, School of Medicine, University of Galway, H91 YR71 Galway, IrelandFaculty of Engineering, Government College University, Lahore 54000, PakistanLambe Institute for Translational Research, School of Medicine, University of Galway, H91 YR71 Galway, IrelandData augmentation using generative adversarial networks (GANs) is vital in the creation of new instances that include imaging modality tasks for improved deep learning classification. In this study, conditional generative adversarial networks (cGANs) were used on a dataset of OCT (Optical Coherence Tomography)-acquired images of coronary atrial plaques for synthetic data creation for the first time, and further validated using deep learning architecture. A new OCT images dataset of 51 patients marked by three professionals was created and programmed. We used cGANs to synthetically populate the coronary aerial plaques dataset by factors of 5×, 10×, 50× and 100× from a limited original dataset to enhance its volume and diversification. The loss functions for the generator and the discriminator were set up to generate perfect aliases. The augmented OCT dataset was then used in the training phase of the leading AlexNet architecture. We used cGANs to create synthetic images and envisaged the impact of the ratio of real data to synthetic data on classification accuracy. We illustrated through experiments that augmenting real images with synthetic images by a factor of 50× during training helped improve the test accuracy of the classification architecture for label prediction by 15.8%. Further, we performed training time assessments against a number of iterations to identify optimum time efficiency. Automated plaques detection was found to be in conformity with clinical results using our proposed class conditioning GAN architecture.https://www.mdpi.com/2673-3269/4/2/20optical coherence tomographydata augmentationgenerative adversarial networksdeep learningcoronary plaquestraining data
spellingShingle Haroon Zafar
Junaid Zafar
Faisal Sharif
GANs-Based Intracoronary Optical Coherence Tomography Image Augmentation for Improved Plaques Characterization Using Deep Neural Networks
Optics
optical coherence tomography
data augmentation
generative adversarial networks
deep learning
coronary plaques
training data
title GANs-Based Intracoronary Optical Coherence Tomography Image Augmentation for Improved Plaques Characterization Using Deep Neural Networks
title_full GANs-Based Intracoronary Optical Coherence Tomography Image Augmentation for Improved Plaques Characterization Using Deep Neural Networks
title_fullStr GANs-Based Intracoronary Optical Coherence Tomography Image Augmentation for Improved Plaques Characterization Using Deep Neural Networks
title_full_unstemmed GANs-Based Intracoronary Optical Coherence Tomography Image Augmentation for Improved Plaques Characterization Using Deep Neural Networks
title_short GANs-Based Intracoronary Optical Coherence Tomography Image Augmentation for Improved Plaques Characterization Using Deep Neural Networks
title_sort gans based intracoronary optical coherence tomography image augmentation for improved plaques characterization using deep neural networks
topic optical coherence tomography
data augmentation
generative adversarial networks
deep learning
coronary plaques
training data
url https://www.mdpi.com/2673-3269/4/2/20
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