Prevalence of depression and anxiety among myasthenia gravis (MG) patients: A systematic review and meta‐analysis
Abstract Objective Myasthenia gravis (MG) people experience adverse psychiatric outcomes, which may impact on their life and disturb their daily activity. Depression and anxiety are identified as significant psychiatric problems that MG people face. However, there is no sufficient epidemiological in...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-01-01
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| Series: | Brain and Behavior |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/brb3.2840 |
| _version_ | 1797893681554915328 |
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| author | Javad Nadali Neda Ghavampour Farzaneh Beiranvand Mona Maleki Takhtegahi Mohammad Eghbal Heidari Shahin Salarvand Tina Arabzadeh Omid Narimani Charan |
| author_facet | Javad Nadali Neda Ghavampour Farzaneh Beiranvand Mona Maleki Takhtegahi Mohammad Eghbal Heidari Shahin Salarvand Tina Arabzadeh Omid Narimani Charan |
| author_sort | Javad Nadali |
| collection | DOAJ |
| description | Abstract Objective Myasthenia gravis (MG) people experience adverse psychiatric outcomes, which may impact on their life and disturb their daily activity. Depression and anxiety are identified as significant psychiatric problems that MG people face. However, there is no sufficient epidemiological information about depression and anxiety‐based publication. Due to this limitation, the aim of this study was to review the prevalence of depression and anxiety in MG patients. Methods Original and international databases were searched to find papers about the estimation of anxiety and depression. Random‐effects analysis was used for calculating the proportions of anxiety and depression. For estimating anxiety and depression based the severity, instruments, type of studies, and study regions, subgroup analysis was performed. Results 38 studies met inclusion criteria and entered study. The pooling of the prevalence of depression was found at 36%, (95% CI 28% to 45%). Also, prevalence of anxiety was found at 33%, (95% CI 25% to 42%). Prevalence of depression based on mild, moderate, and severe level was 27%, 14%, and 9%, respectively. Conclusions Anxiety and depression are a major concern among MG individuals. The estimation of both anxiety and depression are high even when compared to other autoimmune diseases. It seems depression and anxiety are important issues and more attention needs to be paid to these psychiatric disorders. |
| first_indexed | 2024-04-10T06:56:46Z |
| format | Article |
| id | doaj.art-14649c2bbcb84f99898c88777f7d8711 |
| institution | Directory Open Access Journal |
| issn | 2162-3279 |
| language | English |
| last_indexed | 2024-04-10T06:56:46Z |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Brain and Behavior |
| spelling | doaj.art-14649c2bbcb84f99898c88777f7d87112023-02-28T07:01:06ZengWileyBrain and Behavior2162-32792023-01-01131n/an/a10.1002/brb3.2840Prevalence of depression and anxiety among myasthenia gravis (MG) patients: A systematic review and meta‐analysisJavad Nadali0Neda Ghavampour1Farzaneh Beiranvand2Mona Maleki Takhtegahi3Mohammad Eghbal Heidari4Shahin Salarvand5Tina Arabzadeh6Omid Narimani Charan7School of Nursing and Midwifery Shahroud University of Medical Sciences Shahroud IranSchool of Nursing and Midwifery Tehran University of Medical Sciences Tehran IranSchool of Nursing and Midwifery Tehran University of Medical Sciences Tehran IranSchool of Nursing and Midwifery Tehran University of Medical Sciences Tehran IranStudent's Scientific Research Center, School of Nursing and Midwifery Tehran University of Medical Sciences Tehran IranHepatitis Research Center, Nursing and midwifery faculty Lorestan University of Medical Sciences Lorestan IranSchool of Nursing and Midwifery Tehran University of Medical Sciences Tehran IranSchool of Nursing and Midwifery Tehran University of Medical Sciences Tehran IranAbstract Objective Myasthenia gravis (MG) people experience adverse psychiatric outcomes, which may impact on their life and disturb their daily activity. Depression and anxiety are identified as significant psychiatric problems that MG people face. However, there is no sufficient epidemiological information about depression and anxiety‐based publication. Due to this limitation, the aim of this study was to review the prevalence of depression and anxiety in MG patients. Methods Original and international databases were searched to find papers about the estimation of anxiety and depression. Random‐effects analysis was used for calculating the proportions of anxiety and depression. For estimating anxiety and depression based the severity, instruments, type of studies, and study regions, subgroup analysis was performed. Results 38 studies met inclusion criteria and entered study. The pooling of the prevalence of depression was found at 36%, (95% CI 28% to 45%). Also, prevalence of anxiety was found at 33%, (95% CI 25% to 42%). Prevalence of depression based on mild, moderate, and severe level was 27%, 14%, and 9%, respectively. Conclusions Anxiety and depression are a major concern among MG individuals. The estimation of both anxiety and depression are high even when compared to other autoimmune diseases. It seems depression and anxiety are important issues and more attention needs to be paid to these psychiatric disorders.https://doi.org/10.1002/brb3.2840anxietydepressionMGsystematic review |
| spellingShingle | Javad Nadali Neda Ghavampour Farzaneh Beiranvand Mona Maleki Takhtegahi Mohammad Eghbal Heidari Shahin Salarvand Tina Arabzadeh Omid Narimani Charan Prevalence of depression and anxiety among myasthenia gravis (MG) patients: A systematic review and meta‐analysis Brain and Behavior anxiety depression MG systematic review |
| title | Prevalence of depression and anxiety among myasthenia gravis (MG) patients: A systematic review and meta‐analysis |
| title_full | Prevalence of depression and anxiety among myasthenia gravis (MG) patients: A systematic review and meta‐analysis |
| title_fullStr | Prevalence of depression and anxiety among myasthenia gravis (MG) patients: A systematic review and meta‐analysis |
| title_full_unstemmed | Prevalence of depression and anxiety among myasthenia gravis (MG) patients: A systematic review and meta‐analysis |
| title_short | Prevalence of depression and anxiety among myasthenia gravis (MG) patients: A systematic review and meta‐analysis |
| title_sort | prevalence of depression and anxiety among myasthenia gravis mg patients a systematic review and meta analysis |
| topic | anxiety depression MG systematic review |
| url | https://doi.org/10.1002/brb3.2840 |
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