Complex Tumor Spheroid Formation and One-Step Cancer-Associated Fibroblasts Purification from Hepatocellular Carcinoma Tissue Promoted by Inorganic Surface Topography

Complex Tumor Spheroid Formation and One-Step Cancer-Associated Fibroblasts Purification from Hepatocellular Carcinoma Tissue Promoted by Inorganic Surface Topography

In vitro cell models play important roles as testbeds for toxicity studies, drug development, or as replacements in animal experiments. In particular, complex tumor models such as hepatocellular carcinoma (HCC) are needed to predict drug efficacy and facilitate translation into clinical practice. In...

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Bibliographic Details
Main Authors: Francesco Dituri, Matteo Centonze, Erwin J. W. Berenschot, Niels R. Tas, Arturo Susarrey-Arce, Silke Krol
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Nanomaterials
Subjects:
hepatocellular carcinoma
cancer-associated fibroblast
tumor spheroids
structured surface
cell culture
in vitro tumor models
Online Access:https://www.mdpi.com/2079-4991/11/12/3233

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https://www.mdpi.com/2079-4991/11/12/3233

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