Fluorescent CXCR4 targeting peptide as alternative for antibody staining in Ewing sarcoma

Fluorescent CXCR4 targeting peptide as alternative for antibody staining in Ewing sarcoma

Abstract Background Ewing sarcoma is an aggressive, highly metastatic primary bone and soft tissue tumor most frequently occurring in the bone of young adolescents. Patients, especially those diagnosed with a metastatic disease, have a poor overall survival. Chemokine receptor CXCR4 has a key pro-tu...

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Bibliographic Details
Main Authors: Laurens G. L. Sand, Tessa Buckle, Fijs W. B. van Leeuwen, Willem E. Corver, Alwine B. Kruisselbrink, Aart G. Jochemsen, Pancras C. W. Hogendoorn, Károly Szuhai
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Cancer
Subjects:
Chemokines
Bone tumor
Sarcoma
Molecular imaging
Flow cytometry
Peptides
Online Access:http://link.springer.com/article/10.1186/s12885-017-3352-z

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