Giant pilomatrix carcinoma of the scalp with intracranial extension: A case report
Key Clinical Message A very rare skin cancer. Malignant variant of pilomatricoma. It is unique because of its highly aggressive behavior. Responds poorly to chemotherapy and radiotherapy. Treated with a wide surgical excision with safe margins. Abstract Pilomatrix carcinoma is uncommon and locally a...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-11-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.8123 |
| _version_ | 1797449738230956032 |
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| author | Kenneth Mlay Peter Shija Marco Magwizi Ezekiel G. Karuga Philbert Mtenga Alex Mremi |
| author_facet | Kenneth Mlay Peter Shija Marco Magwizi Ezekiel G. Karuga Philbert Mtenga Alex Mremi |
| author_sort | Kenneth Mlay |
| collection | DOAJ |
| description | Key Clinical Message A very rare skin cancer. Malignant variant of pilomatricoma. It is unique because of its highly aggressive behavior. Responds poorly to chemotherapy and radiotherapy. Treated with a wide surgical excision with safe margins. Abstract Pilomatrix carcinoma is uncommon and locally aggressive tumor of the hair follicle matrix. It is a malignant variant of pilomatricoma. If left untreated for a long time may attain massive size and has the potential for distant spread. Only few cases with brain extension have been reported in the literature. Diagnosis of these tumors is established by histopathology. Although pilomatrixoma and pilomatrix carcinoma are well‐recognized lesions, clinically they are frequently misdiagnosed as other skin conditions. The tumors respond poorly to chemotherapy and radiotherapy. Thus, recommended treatment is a wide surgical excision with safe margins. Herein, we report the case of a 39‐year‐old African woman with pilomatrix carcinoma of the scalp eroding the skull bone with intracranial extension. |
| first_indexed | 2024-03-09T14:29:26Z |
| format | Article |
| id | doaj.art-14667f4a0ff041989debfc8c677cc012 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-03-09T14:29:26Z |
| publishDate | 2023-11-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-14667f4a0ff041989debfc8c677cc0122023-11-28T04:14:44ZengWileyClinical Case Reports2050-09042023-11-011111n/an/a10.1002/ccr3.8123Giant pilomatrix carcinoma of the scalp with intracranial extension: A case reportKenneth Mlay0Peter Shija1Marco Magwizi2Ezekiel G. Karuga3Philbert Mtenga4Alex Mremi5Department of Otorhinolaryngology Kilimanjaro Christian Medical Centre Moshi TanzaniaDepartment of Otorhinolaryngology Kilimanjaro Christian Medical Centre Moshi TanzaniaDepartment of Otorhinolaryngology Kilimanjaro Christian Medical Centre Moshi TanzaniaDepartment of Otorhinolaryngology Kilimanjaro Christian Medical Centre Moshi TanzaniaDepartment of Otorhinolaryngology Kilimanjaro Christian Medical Centre Moshi TanzaniaFaculty of Medicine Kilimanjaro Christian Medical University College Moshi TanzaniaKey Clinical Message A very rare skin cancer. Malignant variant of pilomatricoma. It is unique because of its highly aggressive behavior. Responds poorly to chemotherapy and radiotherapy. Treated with a wide surgical excision with safe margins. Abstract Pilomatrix carcinoma is uncommon and locally aggressive tumor of the hair follicle matrix. It is a malignant variant of pilomatricoma. If left untreated for a long time may attain massive size and has the potential for distant spread. Only few cases with brain extension have been reported in the literature. Diagnosis of these tumors is established by histopathology. Although pilomatrixoma and pilomatrix carcinoma are well‐recognized lesions, clinically they are frequently misdiagnosed as other skin conditions. The tumors respond poorly to chemotherapy and radiotherapy. Thus, recommended treatment is a wide surgical excision with safe margins. Herein, we report the case of a 39‐year‐old African woman with pilomatrix carcinoma of the scalp eroding the skull bone with intracranial extension.https://doi.org/10.1002/ccr3.8123case reportmalignant pilomatrixomapilomatrix carcinomarecurrenceskin cancerwide local excision |
| spellingShingle | Kenneth Mlay Peter Shija Marco Magwizi Ezekiel G. Karuga Philbert Mtenga Alex Mremi Giant pilomatrix carcinoma of the scalp with intracranial extension: A case report Clinical Case Reports case report malignant pilomatrixoma pilomatrix carcinoma recurrence skin cancer wide local excision |
| title | Giant pilomatrix carcinoma of the scalp with intracranial extension: A case report |
| title_full | Giant pilomatrix carcinoma of the scalp with intracranial extension: A case report |
| title_fullStr | Giant pilomatrix carcinoma of the scalp with intracranial extension: A case report |
| title_full_unstemmed | Giant pilomatrix carcinoma of the scalp with intracranial extension: A case report |
| title_short | Giant pilomatrix carcinoma of the scalp with intracranial extension: A case report |
| title_sort | giant pilomatrix carcinoma of the scalp with intracranial extension a case report |
| topic | case report malignant pilomatrixoma pilomatrix carcinoma recurrence skin cancer wide local excision |
| url | https://doi.org/10.1002/ccr3.8123 |
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