Methanolic rhizome extract of Trillium govanianum coated gold nanoparticles: Facile biogenic synthesis, their characterisation, and potential antimicrobial study
Abstract The scientific community is endowed with the essential biogenic, eco‐benign, and cost‐effective synthesis of gold nanoparticles (AuNPs) of least explored Trillium govanianum methanolic extract. The study involved T. govanianum selection based on its tremendous therapeutic properties. These...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-09-01
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| Series: | Micro & Nano Letters |
| Online Access: | https://doi.org/10.1049/mna2.12129 |
| _version_ | 1828152640007045120 |
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| author | Khaleeq‐Uz Zaman Jehan Bakht Adil A.H. Mujawah Abdur Rauf Muhammad Sharif Aneela Maalik |
| author_facet | Khaleeq‐Uz Zaman Jehan Bakht Adil A.H. Mujawah Abdur Rauf Muhammad Sharif Aneela Maalik |
| author_sort | Khaleeq‐Uz Zaman |
| collection | DOAJ |
| description | Abstract The scientific community is endowed with the essential biogenic, eco‐benign, and cost‐effective synthesis of gold nanoparticles (AuNPs) of least explored Trillium govanianum methanolic extract. The study involved T. govanianum selection based on its tremendous therapeutic properties. These AuNPs were characterised by UV–visible spectroscope, atomic force electron microscope, scanning electron microscope (SEM), FTIR spectroscope, and X‐ray diffraction. The atomic force electron microscope pattern revealed that particle size ranges from 2 to 24.3 nm which corresponds to X‐ray diffraction analysis data (8.87–15 nm) with spherical morphology. The spherical nature, particle size distribution, non‐agglomeration, and homogeneity of AuNPs were also studied from SEM image. The diameter range of AuNPs was measured between 20 and 30 nm with an average size of 25 nm. FTIR profile showed that AuNPs were stabilised and capped by bio‐molecules containing aromatic amine functional groups. Amongst C. albicans, Curvularia, R. oryzae, A. niger, A. alternaria, and Paecilomyces fungal strains, AuNPs were found most efficient against C. albicans (53.33%) at 18 μL per disc. While in P. aeroginosa, B. subtilis, E. coli, K. pnemoniae, S. aureus, and X. compestris bacterial strains, AuNPs at 18 μL per disc revealed promising antibacterial potential against P. aeroginosa by displaying maximum inhibition of 66.66 %. |
| first_indexed | 2024-04-11T22:14:15Z |
| format | Article |
| id | doaj.art-1467d48b8b7c46079e6a539ccccc0e29 |
| institution | Directory Open Access Journal |
| issn | 1750-0443 |
| language | English |
| last_indexed | 2024-04-11T22:14:15Z |
| publishDate | 2022-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Micro & Nano Letters |
| spelling | doaj.art-1467d48b8b7c46079e6a539ccccc0e292022-12-22T04:00:28ZengWileyMicro & Nano Letters1750-04432022-09-01171024225110.1049/mna2.12129Methanolic rhizome extract of Trillium govanianum coated gold nanoparticles: Facile biogenic synthesis, their characterisation, and potential antimicrobial studyKhaleeq‐Uz Zaman0Jehan Bakht1Adil A.H. Mujawah2Abdur Rauf3Muhammad Sharif4Aneela Maalik5Institute of Biotechnology and Genetic Engineering University of Agriculture Peshawar Khyber Pakhtunkhwa PakistanInstitute of Biotechnology and Genetic Engineering University of Agriculture Peshawar Khyber Pakhtunkhwa PakistanDepartment of Chemistry College of Science and Arts Qasim University Ar Rass Saudi ArabiaDepartment of Chemistry University of Swabi Anbar Khyber Pakhtunkhwa PakistanDepartment of Chemistry King Fahd University of Petroleum & Minerals Dhahran Saudi ArabiaDepartment of Chemistry COMSATS University Islamabad Islamabad Campus, Park Road Islamabad PakistanAbstract The scientific community is endowed with the essential biogenic, eco‐benign, and cost‐effective synthesis of gold nanoparticles (AuNPs) of least explored Trillium govanianum methanolic extract. The study involved T. govanianum selection based on its tremendous therapeutic properties. These AuNPs were characterised by UV–visible spectroscope, atomic force electron microscope, scanning electron microscope (SEM), FTIR spectroscope, and X‐ray diffraction. The atomic force electron microscope pattern revealed that particle size ranges from 2 to 24.3 nm which corresponds to X‐ray diffraction analysis data (8.87–15 nm) with spherical morphology. The spherical nature, particle size distribution, non‐agglomeration, and homogeneity of AuNPs were also studied from SEM image. The diameter range of AuNPs was measured between 20 and 30 nm with an average size of 25 nm. FTIR profile showed that AuNPs were stabilised and capped by bio‐molecules containing aromatic amine functional groups. Amongst C. albicans, Curvularia, R. oryzae, A. niger, A. alternaria, and Paecilomyces fungal strains, AuNPs were found most efficient against C. albicans (53.33%) at 18 μL per disc. While in P. aeroginosa, B. subtilis, E. coli, K. pnemoniae, S. aureus, and X. compestris bacterial strains, AuNPs at 18 μL per disc revealed promising antibacterial potential against P. aeroginosa by displaying maximum inhibition of 66.66 %.https://doi.org/10.1049/mna2.12129 |
| spellingShingle | Khaleeq‐Uz Zaman Jehan Bakht Adil A.H. Mujawah Abdur Rauf Muhammad Sharif Aneela Maalik Methanolic rhizome extract of Trillium govanianum coated gold nanoparticles: Facile biogenic synthesis, their characterisation, and potential antimicrobial study Micro & Nano Letters |
| title | Methanolic rhizome extract of Trillium govanianum coated gold nanoparticles: Facile biogenic synthesis, their characterisation, and potential antimicrobial study |
| title_full | Methanolic rhizome extract of Trillium govanianum coated gold nanoparticles: Facile biogenic synthesis, their characterisation, and potential antimicrobial study |
| title_fullStr | Methanolic rhizome extract of Trillium govanianum coated gold nanoparticles: Facile biogenic synthesis, their characterisation, and potential antimicrobial study |
| title_full_unstemmed | Methanolic rhizome extract of Trillium govanianum coated gold nanoparticles: Facile biogenic synthesis, their characterisation, and potential antimicrobial study |
| title_short | Methanolic rhizome extract of Trillium govanianum coated gold nanoparticles: Facile biogenic synthesis, their characterisation, and potential antimicrobial study |
| title_sort | methanolic rhizome extract of trillium govanianum coated gold nanoparticles facile biogenic synthesis their characterisation and potential antimicrobial study |
| url | https://doi.org/10.1049/mna2.12129 |
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