Immunomodulation of gastrointestinal tract by probiotics: an insight into the role of Lactobacillus sp. and Bacillus sp. on immunity
The gastrointestinal tract (GIT) is an immunologically active ecosystem with a crucial role in activating or stimulating the immune system as well as a barrier against microbial antigens. About a hundredtrillion microorganisms such as bacteria, viruses, fungi, and protozoa cohabit with...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Plovdiv University Press
2023-07-01
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| Series: | Journal of BioScience and Biotechnology |
| Subjects: | |
| Online Access: | https://editorial.uni-plovdiv.bg/index.php/JBB/article/view/444/323 |
| Summary: | The gastrointestinal tract (GIT) is an immunologically active ecosystem with a crucial role in activating or stimulating the immune system as well as a barrier against microbial antigens. About a hundredtrillion microorganisms such as bacteria, viruses, fungi, and protozoa cohabit with the GIT. Gut microbes play a vital role in health and disease, leading to the emergence of ‘probiotics’ a novel therapeutic consumption of live, beneficial cultures. Probiotics exhibit an extensive mechanism of action which include destroying/blocking pathogens, production of antimicrobial compounds, and modulation of the immune system without affecting intestinal homeostasis. Although Lactobacillussp. is most abundantly used as a probiotic, reports also show the emergence of Bacillussp. in boosting the immune system and promoting good health. This review attempts to highlight the potential of Lactobacillus and Bacillus species as a probiotic in stimulating the immune system. |
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| ISSN: | 1314-6238 1314-6246 |