Polygenic Risk Score in African populations: progress and challenges [version 2; peer review: 2 approved]

Polygenic Risk Score in African populations: progress and challenges [version 2; peer review: 2 approved]

Polygenic Risk Score (PRS) analysis is a method that predicts the genetic risk of an individual towards targeted traits. Even when there are no significant markers, it gives evidence of a genetic effect beyond the results of Genome-Wide Association Studies (GWAS). Moreover, it selects  single nucleo...

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Bibliographic Details
Main Authors: Rotimi Solomon, Gordon Wells, Benedikt Brors, Emmanuel Adetiba, Yagoub Adam, Ezekiel Adebiyi, Olabode Ajayi, Suraju Sadeeq, Olubanke Ogunlana, Judit Kumuthini, Emeka Iweala
Format: Article
Language:English
Published: F1000 Research Ltd 2023-04-01
Series:F1000Research
Subjects:
Prediction medicine
GWAS
post-GWAS
PRS analysis
Africa population
eng
Online Access:https://f1000research.com/articles/11-175/v2

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