Clinical Course of SARS CoV-2 Infection in Hospitalized Pregnant Patients
Objective: To determine the clinical course and outcome of hospitalized pregnant patients with laboratory confirmed SARS CoV-2 (COVID-19) infection Study Design: Prospective longitudinal study Place and Duration of Study: Obstetrics Units of Pak Emirates Military Hospital and Combined Militar...
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| Format: | Article |
| Language: | English |
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Army Medical College Rawalpindi
2022-12-01
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| Series: | Pakistan Armed Forces Medical Journal |
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| Online Access: | https://pafmj.org/index.php/PAFMJ/article/view/4512 |
| _version_ | 1797938511279554560 |
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| author | Asma Ansari Asifa Siraj Sumaira Khan Rabiya Jalil Abeera Choudary Hafsa Khalil |
| author_facet | Asma Ansari Asifa Siraj Sumaira Khan Rabiya Jalil Abeera Choudary Hafsa Khalil |
| author_sort | Asma Ansari |
| collection | DOAJ |
| description |
Objective: To determine the clinical course and outcome of hospitalized pregnant patients with laboratory confirmed SARS CoV-2 (COVID-19) infection
Study Design: Prospective longitudinal study
Place and Duration of Study: Obstetrics Units of Pak Emirates Military Hospital and Combined Military Hospital, Rawalpindi Pakistan, from May to Jun 2020.
Methodology: All patients reporting for childbirth were tested for SARS-CoV-2, and those testing positive were included. The primary outcome was virus clearance time and categorization according to the severity of the disease into asymptomatic,mild, moderate, severe and critical. Furthermore, a comparison was made between the presence of comorbid conditions and symptoms in the category of COVID-19. In addition, neonatal sample evaluation for SARS-CoV-2 was done.
Results: Out of the 881 women giving birth, 41(4.6%) tested positive for SARS Cov-2. Majority were asymptomatic 28(68.3%)followed by mild 8(19.5%), moderate 4(9.8%) and severe 1(2.4%) category. There was a significant association of the COVID categories with symptoms (p-value<0.005) and comorbid condition (p-value<0.001). The mean virus clearance time was 8.20±1.66 days. During hospital stay 34(82.9%) delivered. All 34(100%) delivered babies had no evidence of vertical transmission.
Conclusion: Pregnant women with COVID-19 infection have a nearly similar clinical course to non-COVID women in this study. There is also no evidence of vertical transmission to the neonate.
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| first_indexed | 2024-04-10T19:01:56Z |
| format | Article |
| id | doaj.art-147bd811e7af433c9f51d7ec7e43dd6d |
| institution | Directory Open Access Journal |
| issn | 0030-9648 2411-8842 |
| language | English |
| last_indexed | 2024-04-10T19:01:56Z |
| publishDate | 2022-12-01 |
| publisher | Army Medical College Rawalpindi |
| record_format | Article |
| series | Pakistan Armed Forces Medical Journal |
| spelling | doaj.art-147bd811e7af433c9f51d7ec7e43dd6d2023-01-31T08:20:39ZengArmy Medical College RawalpindiPakistan Armed Forces Medical Journal0030-96482411-88422022-12-0172610.51253/pafmj.v72i6.4512Clinical Course of SARS CoV-2 Infection in Hospitalized Pregnant PatientsAsma Ansari0Asifa Siraj1Sumaira Khan2Rabiya Jalil3Abeera Choudary4Hafsa Khalil5Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanPak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanPak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanCombined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanNational University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Force Institute of Cardiology/National Institute of Heart Disease (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi Pakistan Objective: To determine the clinical course and outcome of hospitalized pregnant patients with laboratory confirmed SARS CoV-2 (COVID-19) infection Study Design: Prospective longitudinal study Place and Duration of Study: Obstetrics Units of Pak Emirates Military Hospital and Combined Military Hospital, Rawalpindi Pakistan, from May to Jun 2020. Methodology: All patients reporting for childbirth were tested for SARS-CoV-2, and those testing positive were included. The primary outcome was virus clearance time and categorization according to the severity of the disease into asymptomatic,mild, moderate, severe and critical. Furthermore, a comparison was made between the presence of comorbid conditions and symptoms in the category of COVID-19. In addition, neonatal sample evaluation for SARS-CoV-2 was done. Results: Out of the 881 women giving birth, 41(4.6%) tested positive for SARS Cov-2. Majority were asymptomatic 28(68.3%)followed by mild 8(19.5%), moderate 4(9.8%) and severe 1(2.4%) category. There was a significant association of the COVID categories with symptoms (p-value<0.005) and comorbid condition (p-value<0.001). The mean virus clearance time was 8.20±1.66 days. During hospital stay 34(82.9%) delivered. All 34(100%) delivered babies had no evidence of vertical transmission. Conclusion: Pregnant women with COVID-19 infection have a nearly similar clinical course to non-COVID women in this study. There is also no evidence of vertical transmission to the neonate. https://pafmj.org/index.php/PAFMJ/article/view/4512Clinical courseCOVID-19NeonatalPregnancy |
| spellingShingle | Asma Ansari Asifa Siraj Sumaira Khan Rabiya Jalil Abeera Choudary Hafsa Khalil Clinical Course of SARS CoV-2 Infection in Hospitalized Pregnant Patients Pakistan Armed Forces Medical Journal Clinical course COVID-19 Neonatal Pregnancy |
| title | Clinical Course of SARS CoV-2 Infection in Hospitalized Pregnant Patients |
| title_full | Clinical Course of SARS CoV-2 Infection in Hospitalized Pregnant Patients |
| title_fullStr | Clinical Course of SARS CoV-2 Infection in Hospitalized Pregnant Patients |
| title_full_unstemmed | Clinical Course of SARS CoV-2 Infection in Hospitalized Pregnant Patients |
| title_short | Clinical Course of SARS CoV-2 Infection in Hospitalized Pregnant Patients |
| title_sort | clinical course of sars cov 2 infection in hospitalized pregnant patients |
| topic | Clinical course COVID-19 Neonatal Pregnancy |
| url | https://pafmj.org/index.php/PAFMJ/article/view/4512 |
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