Bacterial vaginosis and other infections in pregnant women in Senegal
Abstract Background Bacterial vaginosis (BV) is associated with a higher risk of preterm delivery and spontaneous abortion. Yet little data on BV prevalence exist for sub-Saharan countries. The aim of this study was to estimate the prevalence of bacterial vaginosis and associated risk factors among...
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| Format: | Article |
| Language: | English |
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BMC
2021-10-01
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| Series: | BMC Infectious Diseases |
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| Online Access: | https://doi.org/10.1186/s12879-021-06767-4 |
| _version_ | 1818979199919063040 |
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| author | Marion Bonneton Bich-Tram Huynh Abdoulaye Seck Raymond Bercion Fatoumata Diene Sarr Elisabeth Delarocque-Astagneau Muriel Vray |
| author_facet | Marion Bonneton Bich-Tram Huynh Abdoulaye Seck Raymond Bercion Fatoumata Diene Sarr Elisabeth Delarocque-Astagneau Muriel Vray |
| author_sort | Marion Bonneton |
| collection | DOAJ |
| description | Abstract Background Bacterial vaginosis (BV) is associated with a higher risk of preterm delivery and spontaneous abortion. Yet little data on BV prevalence exist for sub-Saharan countries. The aim of this study was to estimate the prevalence of bacterial vaginosis and associated risk factors among pregnant women in Senegal. Methods From October 2013 to December 2018, pregnant women in their third trimester were recruited in two primary health centers (one suburban, one rural) in Senegal. Healthcare workers interviewed women and collected a lower vaginal swab and a blood sample. Vaginal flora were classified into four categories using vaginal smear microscopic examination and Gram’s coloration. In our study, BV was defined as vaginal flora with no Lactobacillus spp. Variables associated with BV were analyzed using STATA® through univariate and multivariate analysis. Results A total of 457 women provided a vaginal sample for analysis. Overall, BV prevalence was 18.6% (85/457) [95% CI 15.4–22.6]) and was similar in suburban and rural areas (18.9% versus 18.1%, p = 0.843). Multivariate analysis showed that primigravidity was the only factor independently associated with a lower risk of BV (aOR 0.35 [95% CI 0.17–0.72]). Conclusions Our study showed significant BV prevalence among pregnant women in Senegal. Although the literature has underscored the potential consequences of BV for obstetric outcomes, data are scarce on BV prevalence in sub-Saharan African countries. Before authorities consider systematic BV screening for pregnant women, a larger study would be useful in documenting prevalence, risk factors and the impact of BV on pregnancy outcomes. |
| first_indexed | 2024-12-20T16:55:45Z |
| format | Article |
| id | doaj.art-147c77f543634c27ab324c06e02abd7a |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-12-20T16:55:45Z |
| publishDate | 2021-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-147c77f543634c27ab324c06e02abd7a2022-12-21T19:32:44ZengBMCBMC Infectious Diseases1471-23342021-10-012111710.1186/s12879-021-06767-4Bacterial vaginosis and other infections in pregnant women in SenegalMarion Bonneton0Bich-Tram Huynh1Abdoulaye Seck2Raymond Bercion3Fatoumata Diene Sarr4Elisabeth Delarocque-Astagneau5Muriel Vray6Epidemiology of Infectious Diseases Unit, Institut Pasteur de DakarPharmacoepidemiology and Infectious Diseases Unit, Institut PasteurExperimental Bacteriology Unit, Institut Pasteur de DakarMedical Biology Laboratory, Institut Pasteur de DakarEpidemiology of Infectious Diseases Unit, Institut Pasteur de DakarPharmacoepidemiology and Infectious Diseases Unit, Institut PasteurEpidemiology of Infectious Diseases Unit, Institut Pasteur de DakarAbstract Background Bacterial vaginosis (BV) is associated with a higher risk of preterm delivery and spontaneous abortion. Yet little data on BV prevalence exist for sub-Saharan countries. The aim of this study was to estimate the prevalence of bacterial vaginosis and associated risk factors among pregnant women in Senegal. Methods From October 2013 to December 2018, pregnant women in their third trimester were recruited in two primary health centers (one suburban, one rural) in Senegal. Healthcare workers interviewed women and collected a lower vaginal swab and a blood sample. Vaginal flora were classified into four categories using vaginal smear microscopic examination and Gram’s coloration. In our study, BV was defined as vaginal flora with no Lactobacillus spp. Variables associated with BV were analyzed using STATA® through univariate and multivariate analysis. Results A total of 457 women provided a vaginal sample for analysis. Overall, BV prevalence was 18.6% (85/457) [95% CI 15.4–22.6]) and was similar in suburban and rural areas (18.9% versus 18.1%, p = 0.843). Multivariate analysis showed that primigravidity was the only factor independently associated with a lower risk of BV (aOR 0.35 [95% CI 0.17–0.72]). Conclusions Our study showed significant BV prevalence among pregnant women in Senegal. Although the literature has underscored the potential consequences of BV for obstetric outcomes, data are scarce on BV prevalence in sub-Saharan African countries. Before authorities consider systematic BV screening for pregnant women, a larger study would be useful in documenting prevalence, risk factors and the impact of BV on pregnancy outcomes.https://doi.org/10.1186/s12879-021-06767-4Bacterial vaginosisVaginal microbiomePregnant women |
| spellingShingle | Marion Bonneton Bich-Tram Huynh Abdoulaye Seck Raymond Bercion Fatoumata Diene Sarr Elisabeth Delarocque-Astagneau Muriel Vray Bacterial vaginosis and other infections in pregnant women in Senegal BMC Infectious Diseases Bacterial vaginosis Vaginal microbiome Pregnant women |
| title | Bacterial vaginosis and other infections in pregnant women in Senegal |
| title_full | Bacterial vaginosis and other infections in pregnant women in Senegal |
| title_fullStr | Bacterial vaginosis and other infections in pregnant women in Senegal |
| title_full_unstemmed | Bacterial vaginosis and other infections in pregnant women in Senegal |
| title_short | Bacterial vaginosis and other infections in pregnant women in Senegal |
| title_sort | bacterial vaginosis and other infections in pregnant women in senegal |
| topic | Bacterial vaginosis Vaginal microbiome Pregnant women |
| url | https://doi.org/10.1186/s12879-021-06767-4 |
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