DNA end resection and its role in DNA replication and DSB repair choice in mammalian cells
DNA repair: tying up loose ends Carefully regulated enzymatic processing of the ends of DNA strands is essential for efficient replication and damage repair while also minimizing the risk of genomic instability. Replication and repair depend on a mechanism known as DNA resection, in which enzymes tr...
Main Authors: | Fei Zhao, Wootae Kim, Jake A. Kloeber, Zhenkun Lou |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-10-01
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Series: | Experimental and Molecular Medicine |
Online Access: | https://doi.org/10.1038/s12276-020-00519-1 |
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