Gas6/TAM Signalling Negatively Regulates Inflammatory Induction of GM-CSF in Mouse Brain Microglia

Gas6/TAM Signalling Negatively Regulates Inflammatory Induction of GM-CSF in Mouse Brain Microglia

Microglia and astrocytes are the main CNS glial cells responsible for the neuroinflammatory response, where they release a plethora of cytokines into the CNS inflammatory milieu. The TAM (Tyro3, Axl, Mer) receptors and their main ligand Gas6 are regulators of this response, however, the underlying m...

Full description

Bibliographic Details
Main Authors: Shannon E. Gilchrist, Grace M. Pennelli, Sassan Hafizi
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
microglia
astrocytes
glial cells
GM-CSF
Gas6
TAM receptors
Online Access:https://www.mdpi.com/2073-4409/10/12/3281

Similar Items

Similar Items