Targeting the YXXΦ Motifs of the SARS Coronaviruses 1 and 2 ORF3a Peptides by In Silico Analysis to Predict Novel Virus—Host Interactions

Targeting the YXXΦ Motifs of the SARS Coronaviruses 1 and 2 ORF3a Peptides by In Silico Analysis to Predict Novel Virus—Host Interactions

The emerging SARS-CoV and SARS-CoV-2 belong to the family of “common cold” RNA coronaviruses, and they are responsible for the 2003 epidemic and the current pandemic with over 6.3 M deaths worldwide. The ORF3a gene is conserved in both viruses and codes for the accessory protein ORF3a, with unclear...

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Bibliographic Details
Main Authors: Athanassios Kakkanas, Eirini Karamichali, Efthymia Ioanna Koufogeorgou, Stathis D. Kotsakis, Urania Georgopoulou, Pelagia Foka
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Biomolecules
Subjects:
SARS-CoV
SARS-CoV-2
ORF3a
YXXΦ motif
post-translational modifications
immune response
Online Access:https://www.mdpi.com/2218-273X/12/8/1052

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